Expression of STARD13 in cancer - Summary

CANCER ATLAS

Gene description

StAR-related lipid transfer (START) domain containing 13

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA039535	HPA058867

GENE INFORMATION
Gene name	STARD13 (HGNC Symbol)
Synonyms	ARHGAP37, DLC2, GT650, LINC00464
Description	StAR-related lipid transfer (START) domain containing 13 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Chromosome	13
Cytoband	q13.1
Chromosome location (bp)	33103135 - 33350630
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000133121 (version 83.38)
Entrez gene	90627
UniProt	Q9Y3M8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y3M8
Antibodypedia	STARD13 antibodies

PROTEIN BROWSER

STARD13-001	STARD13-003	STARD13-006	STARD13-007	STARD13-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STARD13-001 ENSP00000382300 ENST00000399365	Q9Y3M8 [Direct mapping] StAR-related lipid transfer protein 13 B2R789 [Target identity:100%; Query identity:100%] START domain containing 13, isoform CRA_b; cDNA, FLJ93332, Homo sapiens START domain containing 13 (STARD13), transcriptvariant gamma, mRNA Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005811 [lipid particle] GO:0005829 [cytosol] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0008289 [lipid binding] GO:0031966 [mitochondrial membrane] GO:0043547 [positive regulation of GTPase activity] GO:0051056 [regulation of small GTPase mediated signal transduction] Show all	995 aa 111.2 kDa	No	0
STARD13-003 ENSP00000255486 ENST00000255486	Q9Y3M8 [Direct mapping] StAR-related lipid transfer protein 13 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005811 [lipid particle] GO:0005829 [cytosol] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0008289 [lipid binding] GO:0031966 [mitochondrial membrane] GO:0043547 [positive regulation of GTPase activity] GO:0051056 [regulation of small GTPase mediated signal transduction] Show all	1105 aa 123.9 kDa	No	0
STARD13-006 ENSP00000338785 ENST00000336934	Q9Y3M8 [Direct mapping] StAR-related lipid transfer protein 13 A0A024RDV4 [Target identity:100%; Query identity:100%] START domain containing 13, isoform CRA_a Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005811 [lipid particle] GO:0005829 [cytosol] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0008289 [lipid binding] GO:0031966 [mitochondrial membrane] GO:0043547 [positive regulation of GTPase activity] GO:0051056 [regulation of small GTPase mediated signal transduction] Show all	1113 aa 125 kDa	No	0
STARD13-007 ENSP00000456233 ENST00000567873	H3BRG5 [Direct mapping] StAR-related lipid transfer protein 13 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	607 aa 67.2 kDa	No	0
STARD13-008 ENSP00000457840 ENST00000439831	H3BUW7 [Direct mapping] StAR-related lipid transfer protein 13 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		63 aa 7.4 kDa	No	0