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STARD13

GENERAL INFORMATION

Gene name

 STARD13

Gene description

 StAR-related lipid transfer (START) domain containing 13

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA039535 , HPA058867
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 STARD13 (HGNC Symbol)

Synonyms

 ARHGAP37, DLC2, GT650, LINC00464

Description

 StAR-related lipid transfer (START) domain containing 13 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Chromosome

 13

Cytoband

 q13.1

Chromosome location (bp)

 33103135 - 33350630

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000133121 (version 83.38)

Entrez gene

 90627

UniProt

 Q9Y3M8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y3M8

Antibodypedia

 STARD13 antibodies

PROTEIN BROWSER
STARD13-001
STARD13-003
STARD13-006
STARD13-007
STARD13-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
STARD13-001
ENSP00000382300
ENST00000399365
Q9Y3M8 [Direct mapping]
StAR-related lipid transfer protein 13
B2R789 [Target identity:100%; Query identity:100%]
START domain containing 13, isoform CRA_b; cDNA, FLJ93332, Homo sapiens START domain containing 13 (STARD13), transcriptvariant gamma, mRNA
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005811 [lipid particle]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008289 [lipid binding]
GO:0031966 [mitochondrial membrane]
GO:0043547 [positive regulation of GTPase activity]
GO:0051056 [regulation of small GTPase mediated signal transduction]
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 995 aa
111.2 kDa 		No 0
STARD13-003
ENSP00000255486
ENST00000255486
Q9Y3M8 [Direct mapping]
StAR-related lipid transfer protein 13
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005811 [lipid particle]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008289 [lipid binding]
GO:0031966 [mitochondrial membrane]
GO:0043547 [positive regulation of GTPase activity]
GO:0051056 [regulation of small GTPase mediated signal transduction]
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 1105 aa
123.9 kDa 		No 0
STARD13-006
ENSP00000338785
ENST00000336934
Q9Y3M8 [Direct mapping]
StAR-related lipid transfer protein 13
A0A024RDV4 [Target identity:100%; Query identity:100%]
START domain containing 13, isoform CRA_a
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005811 [lipid particle]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008289 [lipid binding]
GO:0031966 [mitochondrial membrane]
GO:0043547 [positive regulation of GTPase activity]
GO:0051056 [regulation of small GTPase mediated signal transduction]
Show all
 1113 aa
125 kDa 		No 0
STARD13-007
ENSP00000456233
ENST00000567873
H3BRG5 [Direct mapping]
StAR-related lipid transfer protein 13
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
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 607 aa
67.2 kDa 		No 0
STARD13-008
ENSP00000457840
ENST00000439831
H3BUW7 [Direct mapping]
StAR-related lipid transfer protein 13
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 63 aa
7.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.