Cell atlas - SLC2A11 - The Human Protein Atlas

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SLC2A11

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cell Junctions
	Nucleus

Human cell
	Nucleoplasm
	Plasma Membrane

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GENERAL INFORMATION
Gene name	SLC2A11
Gene description	Solute carrier family 2 (facilitated glucose transporter), member 11
Protein class	Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cell junctions. In addition localized to the nucleus.
RNA cell category	Mixed
Protein evidence	Evidence at transcript level
Main location	Localized to the Cell Junctions (uncertain)
Additional location	In addition localized to the Nucleus (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA071184
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cell junctions. In addition localized to the nucleus.

Main location

Cell Junctions (uncertain)

Additional location

Nucleus (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA071184	MCF7	Cell Junctions
	HPA071184	SK-MEL-30	Nucleus
	HPA071184	SK-MEL-30	Cell Junctions
	HPA071184	U-2 OS	Cell Junctions

GENE INFORMATION
Gene name	SLC2A11 (HGNC Symbol)
Synonyms	GLUT10, GLUT11
Description	Solute carrier family 2 (facilitated glucose transporter), member 11 (HGNC Symbol)
Entrez gene summary	This gene belongs to a family of proteins that mediate the transport of sugars across the cell membrane. The encoded protein transports glucose and fructose. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Chromosome	22
Cytoband	q11.23
Chromosome location (bp)	23856703 - 23886309
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000133460 (version 83.38)
Entrez gene	66035
UniProt	Q9BYW1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BYW1
Antibodypedia	SLC2A11 antibodies

PROTEIN BROWSER

SLC2A11-001	SLC2A11-002	SLC2A11-004	SLC2A11-011	SLC2A11-014	SLC2A11-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC2A11-001 ENSP00000342542 ENST00000345044	Q9BYW1 [Direct mapping] Solute carrier family 2, facilitated glucose transporter member 11 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005351 [sugar:proton symporter activity] GO:0005355 [glucose transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0015992 [proton transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0022891 [substrate-specific transmembrane transporter activity] GO:0035428 [hexose transmembrane transport] GO:0046323 [glucose import] GO:0055085 [transmembrane transport] GO:1904659 [glucose transmembrane transport] Show all	496 aa 53.7 kDa	No	>9
SLC2A11-002 ENSP00000381399 ENST00000398356	Q9BYW1 [Direct mapping] Solute carrier family 2, facilitated glucose transporter member 11 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005351 [sugar:proton symporter activity] GO:0005355 [glucose transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0015992 [proton transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0022891 [substrate-specific transmembrane transporter activity] GO:0035428 [hexose transmembrane transport] GO:0046323 [glucose import] GO:0055085 [transmembrane transport] GO:1904659 [glucose transmembrane transport] Show all	503 aa 54.5 kDa	No	>9
SLC2A11-004 ENSP00000326748 ENST00000316185	Q9BYW1 [Direct mapping] Solute carrier family 2, facilitated glucose transporter member 11 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005351 [sugar:proton symporter activity] GO:0005355 [glucose transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0015992 [proton transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0022891 [substrate-specific transmembrane transporter activity] GO:0035428 [hexose transmembrane transport] GO:0046323 [glucose import] GO:0055085 [transmembrane transport] GO:1904659 [glucose transmembrane transport] Show all	499 aa 54 kDa	No	>9
SLC2A11-011 ENSP00000384987 ENST00000405847	B5MCM7 [Direct mapping] Solute carrier family 2, facilitated glucose transporter member 11 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005351 [sugar:proton symporter activity] GO:0005355 [glucose transmembrane transporter activity] GO:0005887 [integral component of plasma membrane] GO:0015992 [proton transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0035428 [hexose transmembrane transport] GO:0046323 [glucose import] GO:0055085 [transmembrane transport] GO:1904659 [glucose transmembrane transport] Show all	179 aa 19.2 kDa	No	5
SLC2A11-014 ENSP00000385949 ENST00000403208	B5MCM1 [Direct mapping] Solute carrier family 2, facilitated glucose transporter member 11 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005351 [sugar:proton symporter activity] GO:0005355 [glucose transmembrane transporter activity] GO:0005887 [integral component of plasma membrane] GO:0015992 [proton transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0035428 [hexose transmembrane transport] GO:0046323 [glucose import] GO:0055085 [transmembrane transport] GO:1904659 [glucose transmembrane transport] Show all	104 aa 11.4 kDa	No	1
SLC2A11-201 ENSP00000483038 ENST00000611880	A0A087X018 [Direct mapping] Solute carrier family 2, facilitated glucose transporter member 11 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005351 [sugar:proton symporter activity] GO:0005355 [glucose transmembrane transporter activity] GO:0005887 [integral component of plasma membrane] GO:0015992 [proton transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0035428 [hexose transmembrane transport] GO:0046323 [glucose import] GO:0055085 [transmembrane transport] GO:1904659 [glucose transmembrane transport] Show all	535 aa 57.1 kDa	No	>9

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.