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Few cases of colorectal cancers showed weak membranous staining. A single case of prostate cancer exhibited moderate positivity. Several cases of gliomas and lung cancers displayed weak to moderate cytoplasmic positivity. Remaining cancer tissues were negative.
A single case of adenocarcinoma of lung showed moderate cytoplasmic positivity. Weak nuclear and cytoplasmic staining was observed in a single case of stomach cancer. All other cancer tissues were negative.
A single case of adenocarcinoma of lung exhibited moderate cytoplasmic immunoreactivity. All other cancer tissues were negative.
GENE INFORMATION
Gene name
SFTPD (HGNC Symbol)
Synonyms
COLEC7, SFTP4, SP-D
Description
Surfactant protein D (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism. [provided by RefSeq, Jul 2015]
P35247 [Direct mapping] Pulmonary surfactant-associated protein D
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Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)