Expression of PEBP4 in cancer - Summary

CANCER ATLAS

Gene description

Phosphatidylethanolamine-binding protein 4

Protein class

Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA025064

GENE INFORMATION
Gene name	PEBP4 (HGNC Symbol)
Synonyms	CORK1, hPEBP4, MGC22776
Description	Phosphatidylethanolamine-binding protein 4 (HGNC Symbol)
Entrez gene summary	The phosphatidylethanolamine (PE)-binding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and inhibition of serine proteases (Wang et al., 2004 [PubMed 15302887]).[supplied by OMIM, Dec 2008]
Chromosome	8
Cytoband	p21.3
Chromosome location (bp)	22713251 - 23000000
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134020 (version 83.38)
Entrez gene	157310
UniProt	Q96S96 (UniProt - Evidence at protein level)
neXtProt	NX_Q96S96
Antibodypedia	PEBP4 antibodies

PROTEIN BROWSER

PEBP4-001	PEBP4-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PEBP4-001 ENSP00000256404 ENST00000256404	Q96S96 [Direct mapping] Phosphatidylethanolamine-binding protein 4 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005764 [lysosome] GO:0070062 [extracellular exosome] Show all	227 aa 25.7 kDa	Yes	0
PEBP4-002 ENSP00000429414 ENST00000522278	E5RIK3 [Direct mapping] Phosphatidylethanolamine-binding protein 4 Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	93 aa 10 kDa	No	0