Tissue expression of PEBP4 - Summary - The Human Protein Atlas

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PEBP4

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	PEBP4
Gene description	Phosphatidylethanolamine-binding protein 4
Protein class	Plasma proteins Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (epididymis, skeletal muscle, lung)
GTEx:	Tissue enhanced (heart muscle, skeletal muscle, lung)
FANTOM5:	Tissue enhanced (skeletal muscle, heart muscle, epididymis)

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA025064
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (epididymis, skeletal muscle, lung)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (heart muscle, skeletal muscle, lung)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (skeletal muscle, heart muscle, epididymis)

GENE INFORMATION
Gene name	PEBP4 (HGNC Symbol)
Synonyms	CORK1, hPEBP4, MGC22776
Description	Phosphatidylethanolamine-binding protein 4 (HGNC Symbol)
Entrez gene summary	The phosphatidylethanolamine (PE)-binding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and inhibition of serine proteases (Wang et al., 2004 [PubMed 15302887]).[supplied by OMIM, Dec 2008]
Chromosome	8
Cytoband	p21.3
Chromosome location (bp)	22713251 - 23000000
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134020 (version 83.38)
Entrez gene	157310
UniProt	Q96S96 (UniProt - Evidence at protein level)
neXtProt	NX_Q96S96
Antibodypedia	PEBP4 antibodies

PROTEIN BROWSER

PEBP4-001	PEBP4-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PEBP4-001 ENSP00000256404 ENST00000256404	Q96S96 [Direct mapping] Phosphatidylethanolamine-binding protein 4 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005764 [lysosome] GO:0070062 [extracellular exosome] Show all	227 aa 25.7 kDa	Yes	0
PEBP4-002 ENSP00000429414 ENST00000522278	E5RIK3 [Direct mapping] Phosphatidylethanolamine-binding protein 4 Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	93 aa 10 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.