Cell atlas - USP30 - The Human Protein Atlas

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USP30

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	USP30
Gene description	Ubiquitin specific peptidase 30
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	USP30 (HGNC Symbol)
Synonyms	FLJ40511, MGC10702
Description	Ubiquitin specific peptidase 30 (HGNC Symbol)
Entrez gene summary	USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008 [PubMed 18287522]).[supplied by OMIM, Dec 2008]
Chromosome	12
Cytoband	q24.11
Chromosome location (bp)	109023089 - 109088026
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000135093 (version 83.38)
Entrez gene	84749
UniProt	Q70CQ3 (UniProt - Evidence at protein level)
neXtProt	NX_Q70CQ3
Antibodypedia	USP30 antibodies

PROTEIN BROWSER

USP30-001	USP30-002	USP30-008	USP30-009	USP30-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
USP30-001 ENSP00000257548 ENST00000257548	Q70CQ3 [Direct mapping] Ubiquitin carboxyl-terminal hydrolase 30 A0A024RBM3 [Target identity:100%; Query identity:100%] Ubiquitin carboxyl-terminal hydrolase Show all	Enzymes ENZYME proteins Hydrolases Peptidases Cysteine-type peptidases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000422 [mitophagy] GO:0004197 [cysteine-type endopeptidase activity] GO:0004843 [ubiquitin-specific protease activity] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005741 [mitochondrial outer membrane] GO:0006511 [ubiquitin-dependent protein catabolic process] GO:0008053 [mitochondrial fusion] GO:0016021 [integral component of membrane] GO:0016579 [protein deubiquitination] GO:0035871 [protein K11-linked deubiquitination] GO:0036459 [ubiquitinyl hydrolase activity] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0044313 [protein K6-linked deubiquitination] GO:0061136 [regulation of proteasomal protein catabolic process] Show all	517 aa 58.5 kDa	No	1
USP30-002 ENSP00000376535 ENST00000392784	B3KUS5 [Direct mapping] Ubiquitin carboxyl-terminal hydrolase Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006511 [ubiquitin-dependent protein catabolic process] GO:0008234 [cysteine-type peptidase activity] GO:0016021 [integral component of membrane] GO:0016579 [protein deubiquitination] GO:0036459 [ubiquitinyl hydrolase activity] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0061136 [regulation of proteasomal protein catabolic process] Show all	486 aa 55.1 kDa	No	0
USP30-008 ENSP00000438829 ENST00000536393	F5H3L3 [Direct mapping] Ubiquitin carboxyl-terminal hydrolase 30 Show all	Phobius predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0016021 [integral component of membrane] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0061136 [regulation of proteasomal protein catabolic process] Show all	146 aa 16.6 kDa	No	0
USP30-009 ENSP00000440837 ENST00000539121	F5GXG2 [Direct mapping] Ubiquitin carboxyl-terminal hydrolase 30 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006511 [ubiquitin-dependent protein catabolic process] GO:0016021 [integral component of membrane] GO:0016579 [protein deubiquitination] GO:0036459 [ubiquitinyl hydrolase activity] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0061136 [regulation of proteasomal protein catabolic process] Show all	95 aa 10.7 kDa	No	1
USP30-010 ENSP00000443678 ENST00000536723	F5H8D3 [Direct mapping] Ubiquitin carboxyl-terminal hydrolase 30 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006511 [ubiquitin-dependent protein catabolic process] GO:0016021 [integral component of membrane] GO:0016579 [protein deubiquitination] GO:0036459 [ubiquitinyl hydrolase activity] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0061136 [regulation of proteasomal protein catabolic process] Show all	177 aa 20.2 kDa	No	1

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.