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Gene name

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In atlas

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Method

Validation

Method

Validation

Method

Validation

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Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

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Score

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Antibodies

Column

 
 
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CD36
  • premium

    TISSUE

  • CELL

  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

CD36 molecule (thrombospondin receptor)

Protein class

Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY

HPA002018
CAB025866

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Malignant tumours were in general negative. One case of breast cancer displayed strong cytoplasmic immunoreactivity.

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

One case of lung cancer showed strong cytoplasmic and membranous staining. Most remaining malignant cells were negative.

GENE INFORMATION

Gene name

CD36 (HGNC Symbol)

Synonyms

FAT, GP3B, GP4, GPIV, SCARB3

Description

CD36 molecule (thrombospondin receptor) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]

Chromosome

7

Cytoband

q21.11

Chromosome location (bp)

80369575 - 80679277

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135218 (version 83.38)

Entrez gene

948

UniProt

P16671 (UniProt - Evidence at protein level)

neXtProt

NX_P16671

Antibodypedia

CD36 antibodies

PROTEIN BROWSER

«
CD36-001
CD36-002
CD36-003
CD36-004
CD36-005
CD36-006
CD36-007
CD36-009
CD36-012
CD36-015
CD36-016
CD36-017
CD36-019
CD36-201
CD36-202
CD36-203
CD36-204
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD36-001
ENSP00000399421
ENST00000435819
P16671 [Direct mapping]
Platelet glycoprotein 4
A4D1B1 [Target identity:100%; Query identity:100%]
CD36 antigen (Collagen type I receptor, thrombospondin receptor); CD36 antigen (Collagen type I receptor, thrombospondin receptor), isoform CRA_a; cDNA, FLJ93369, highly similar to Homo sapiens CD36 antigen (collagen type I receptor, thrombospondinreceptor) (CD36), mRNA
Show all
CD markers
Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001954 [positive regulation of cell-matrix adhesion]
GO:0002221 [pattern recognition receptor signaling pathway]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0002576 [platelet degranulation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0005041 [low-density lipoprotein receptor activity]
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006629 [lipid metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0006910 [phagocytosis, recognition]
GO:0007155 [cell adhesion]
GO:0007166 [cell surface receptor signaling pathway]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0007263 [nitric oxide mediated signal transduction]
GO:0007596 [blood coagulation]
GO:0008035 [high-density lipoprotein particle binding]
GO:0008289 [lipid binding]
GO:0009897 [external side of plasma membrane]
GO:0009986 [cell surface]
GO:0010629 [negative regulation of gene expression]
GO:0010744 [positive regulation of macrophage derived foam cell differentiation]
GO:0010886 [positive regulation of cholesterol storage]
GO:0016020 [membrane]
GO:0019915 [lipid storage]
GO:0019934 [cGMP-mediated signaling]
GO:0030168 [platelet activation]
GO:0030169 [low-density lipoprotein particle binding]
GO:0030194 [positive regulation of blood coagulation]
GO:0030299 [intestinal cholesterol absorption]
GO:0030301 [cholesterol transport]
GO:0030666 [endocytic vesicle membrane]
GO:0031092 [platelet alpha granule membrane]
GO:0031526 [brush border membrane]
GO:0032735 [positive regulation of interleukin-12 production]
GO:0032755 [positive regulation of interleukin-6 production]
GO:0032760 [positive regulation of tumor necrosis factor production]
GO:0033993 [response to lipid]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034197 [triglyceride transport]
GO:0034381 [plasma lipoprotein particle clearance]
GO:0034383 [low-density lipoprotein particle clearance]
GO:0035634 [response to stilbenoid]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042953 [lipoprotein transport]
GO:0042992 [negative regulation of transcription factor import into nucleus]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043277 [apoptotic cell clearance]
GO:0043410 [positive regulation of MAPK cascade]
GO:0044130 [negative regulation of growth of symbiont in host]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0044539 [long-chain fatty acid import]
GO:0045087 [innate immune response]
GO:0045121 [membrane raft]
GO:0045177 [apical part of cell]
GO:0045335 [phagocytic vesicle]
GO:0050431 [transforming growth factor beta binding]
GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation]
GO:0050830 [defense response to Gram-positive bacterium]
GO:0050892 [intestinal absorption]
GO:0050909 [sensory perception of taste]
GO:0055096 [low-density lipoprotein particle mediated signaling]
GO:0060100 [positive regulation of phagocytosis, engulfment]
GO:0060907 [positive regulation of macrophage cytokine production]
GO:0070053 [thrombospondin receptor activity]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070508 [cholesterol import]
GO:0070542 [response to fatty acid]
GO:0070543 [response to linoleic acid]
GO:0070892 [lipoteichoic acid receptor activity]
GO:0071221 [cellular response to bacterial lipopeptide]
GO:0071222 [cellular response to lipopolysaccharide]
GO:0071223 [cellular response to lipoteichoic acid]
GO:0071447 [cellular response to hydroperoxide]
GO:0071813 [lipoprotein particle binding]
GO:2000121 [regulation of removal of superoxide radicals]
GO:2000334 [positive regulation of blood microparticle formation]
GO:2000379 [positive regulation of reactive oxygen species metabolic process]
GO:2000505 [regulation of energy homeostasis]
Show all
472 aa
53.1 kDa
No 2
CD36-002
ENSP00000416388
ENST00000426978
E7EWI4 [Direct mapping]
Platelet glycoprotein 4
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
148 aa
16.2 kDa
No 1
CD36-003
ENSP00000407690
ENST00000413265
E7EX47 [Direct mapping]
Platelet glycoprotein 4
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
203 aa
22.7 kDa
No 1
CD36-004
ENSP00000410371
ENST00000438020
E7ERZ9 [Direct mapping]
Platelet glycoprotein 4
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
143 aa
15.7 kDa
No 1
CD36-005
ENSP00000409762
ENST00000428497
E9PC45 [Direct mapping]
Platelet glycoprotein 4
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
93 aa
10.3 kDa
No 1
CD36-006
ENSP00000308165
ENST00000309881
P16671 [Direct mapping]
Platelet glycoprotein 4
A4D1B1 [Target identity:100%; Query identity:100%]
CD36 antigen (Collagen type I receptor, thrombospondin receptor); CD36 antigen (Collagen type I receptor, thrombospondin receptor), isoform CRA_a; cDNA, FLJ93369, highly similar to Homo sapiens CD36 antigen (collagen type I receptor, thrombospondinreceptor) (CD36), mRNA
Show all
CD markers
Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001954 [positive regulation of cell-matrix adhesion]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0002576 [platelet degranulation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0005041 [low-density lipoprotein receptor activity]
GO:0005615 [extracellular space]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006629 [lipid metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007155 [cell adhesion]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0007263 [nitric oxide mediated signal transduction]
GO:0007596 [blood coagulation]
GO:0008289 [lipid binding]
GO:0009986 [cell surface]
GO:0010744 [positive regulation of macrophage derived foam cell differentiation]
GO:0016020 [membrane]
GO:0019915 [lipid storage]
GO:0019934 [cGMP-mediated signaling]
GO:0030168 [platelet activation]
GO:0030169 [low-density lipoprotein particle binding]
GO:0030299 [intestinal cholesterol absorption]
GO:0030301 [cholesterol transport]
GO:0030666 [endocytic vesicle membrane]
GO:0031092 [platelet alpha granule membrane]
GO:0031526 [brush border membrane]
GO:0033993 [response to lipid]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034197 [triglyceride transport]
GO:0034381 [plasma lipoprotein particle clearance]
GO:0034383 [low-density lipoprotein particle clearance]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042953 [lipoprotein transport]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0044539 [long-chain fatty acid import]
GO:0045087 [innate immune response]
GO:0045335 [phagocytic vesicle]
GO:0050431 [transforming growth factor beta binding]
GO:0050892 [intestinal absorption]
GO:0050909 [sensory perception of taste]
GO:0070053 [thrombospondin receptor activity]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070508 [cholesterol import]
GO:0070542 [response to fatty acid]
GO:0070543 [response to linoleic acid]
GO:0071813 [lipoprotein particle binding]
GO:2000505 [regulation of energy homeostasis]
Show all
472 aa
53.1 kDa
No 2
CD36-007
ENSP00000398760
ENST00000436384
E9PC45 [Direct mapping]
Platelet glycoprotein 4
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
93 aa
10.3 kDa
No 1
CD36-009
ENSP00000433659
ENST00000482059
E9PJX8 [Direct mapping]
Platelet glycoprotein 4
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
65 aa
7 kDa
No 1
CD36-012
ENSP00000392298
ENST00000419819
E7EU05 [Direct mapping]
Platelet glycoprotein 4
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
463 aa
52.1 kDa
No 2
CD36-015
ENSP00000415743
ENST00000447544
P16671 [Direct mapping]
Platelet glycoprotein 4
A4D1B1 [Target identity:100%; Query identity:100%]
CD36 antigen (Collagen type I receptor, thrombospondin receptor); CD36 antigen (Collagen type I receptor, thrombospondin receptor), isoform CRA_a; cDNA, FLJ93369, highly similar to Homo sapiens CD36 antigen (collagen type I receptor, thrombospondinreceptor) (CD36), mRNA
Show all
CD markers
Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001954 [positive regulation of cell-matrix adhesion]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0002576 [platelet degranulation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0005041 [low-density lipoprotein receptor activity]
GO:0005615 [extracellular space]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006629 [lipid metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007155 [cell adhesion]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0007263 [nitric oxide mediated signal transduction]
GO:0007596 [blood coagulation]
GO:0008289 [lipid binding]
GO:0009986 [cell surface]
GO:0010744 [positive regulation of macrophage derived foam cell differentiation]
GO:0016020 [membrane]
GO:0019915 [lipid storage]
GO:0019934 [cGMP-mediated signaling]
GO:0030168 [platelet activation]
GO:0030169 [low-density lipoprotein particle binding]
GO:0030299 [intestinal cholesterol absorption]
GO:0030301 [cholesterol transport]
GO:0030666 [endocytic vesicle membrane]
GO:0031092 [platelet alpha granule membrane]
GO:0031526 [brush border membrane]
GO:0033993 [response to lipid]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034197 [triglyceride transport]
GO:0034381 [plasma lipoprotein particle clearance]
GO:0034383 [low-density lipoprotein particle clearance]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042953 [lipoprotein transport]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0044539 [long-chain fatty acid import]
GO:0045087 [innate immune response]
GO:0045335 [phagocytic vesicle]
GO:0050431 [transforming growth factor beta binding]
GO:0050892 [intestinal absorption]
GO:0050909 [sensory perception of taste]
GO:0070053 [thrombospondin receptor activity]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070508 [cholesterol import]
GO:0070542 [response to fatty acid]
GO:0070543 [response to linoleic acid]
GO:0071813 [lipoprotein particle binding]
GO:2000505 [regulation of energy homeostasis]
Show all
472 aa
53.1 kDa
No 2
CD36-016
ENSP00000378268
ENST00000394788
P16671 [Direct mapping]
Platelet glycoprotein 4
A4D1B1 [Target identity:100%; Query identity:100%]
CD36 antigen (Collagen type I receptor, thrombospondin receptor); CD36 antigen (Collagen type I receptor, thrombospondin receptor), isoform CRA_a; cDNA, FLJ93369, highly similar to Homo sapiens CD36 antigen (collagen type I receptor, thrombospondinreceptor) (CD36), mRNA
Show all
CD markers
Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001954 [positive regulation of cell-matrix adhesion]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0002576 [platelet degranulation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0005041 [low-density lipoprotein receptor activity]
GO:0005615 [extracellular space]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006629 [lipid metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007155 [cell adhesion]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0007263 [nitric oxide mediated signal transduction]
GO:0007596 [blood coagulation]
GO:0008289 [lipid binding]
GO:0009986 [cell surface]
GO:0010744 [positive regulation of macrophage derived foam cell differentiation]
GO:0016020 [membrane]
GO:0019915 [lipid storage]
GO:0019934 [cGMP-mediated signaling]
GO:0030168 [platelet activation]
GO:0030169 [low-density lipoprotein particle binding]
GO:0030299 [intestinal cholesterol absorption]
GO:0030301 [cholesterol transport]
GO:0030666 [endocytic vesicle membrane]
GO:0031092 [platelet alpha granule membrane]
GO:0031526 [brush border membrane]
GO:0033993 [response to lipid]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034197 [triglyceride transport]
GO:0034381 [plasma lipoprotein particle clearance]
GO:0034383 [low-density lipoprotein particle clearance]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042953 [lipoprotein transport]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0044539 [long-chain fatty acid import]
GO:0045087 [innate immune response]
GO:0045335 [phagocytic vesicle]
GO:0050431 [transforming growth factor beta binding]
GO:0050892 [intestinal absorption]
GO:0050909 [sensory perception of taste]
GO:0070053 [thrombospondin receptor activity]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070508 [cholesterol import]
GO:0070542 [response to fatty acid]
GO:0070543 [response to linoleic acid]
GO:0071813 [lipoprotein particle binding]
GO:2000505 [regulation of energy homeostasis]
Show all
472 aa
53.1 kDa
No 2
CD36-017
ENSP00000435698
ENST00000488048
H0YEE7 [Direct mapping]
Platelet glycoprotein 4
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
66 aa
7.3 kDa
No 1
CD36-019
ENSP00000431296
ENST00000534394
E9PLT1 [Direct mapping]
Platelet glycoprotein 4
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007155 [cell adhesion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
396 aa
44.7 kDa
No 1
CD36-201
ENSP00000411411
ENST00000432207
P16671 [Direct mapping]
Platelet glycoprotein 4
A4D1B1 [Target identity:100%; Query identity:100%]
CD36 antigen (Collagen type I receptor, thrombospondin receptor); CD36 antigen (Collagen type I receptor, thrombospondin receptor), isoform CRA_a; cDNA, FLJ93369, highly similar to Homo sapiens CD36 antigen (collagen type I receptor, thrombospondinreceptor) (CD36), mRNA
Show all
CD markers
Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Potential drug targets
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001954 [positive regulation of cell-matrix adhesion]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0002576 [platelet degranulation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0005041 [low-density lipoprotein receptor activity]
GO:0005615 [extracellular space]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006629 [lipid metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007155 [cell adhesion]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0007263 [nitric oxide mediated signal transduction]
GO:0007596 [blood coagulation]
GO:0008289 [lipid binding]
GO:0009986 [cell surface]
GO:0010744 [positive regulation of macrophage derived foam cell differentiation]
GO:0016020 [membrane]
GO:0019915 [lipid storage]
GO:0019934 [cGMP-mediated signaling]
GO:0030168 [platelet activation]
GO:0030169 [low-density lipoprotein particle binding]
GO:0030299 [intestinal cholesterol absorption]
GO:0030301 [cholesterol transport]
GO:0030666 [endocytic vesicle membrane]
GO:0031092 [platelet alpha granule membrane]
GO:0031526 [brush border membrane]
GO:0033993 [response to lipid]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034197 [triglyceride transport]
GO:0034381 [plasma lipoprotein particle clearance]
GO:0034383 [low-density lipoprotein particle clearance]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042953 [lipoprotein transport]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0044539 [long-chain fatty acid import]
GO:0045087 [innate immune response]
GO:0045335 [phagocytic vesicle]
GO:0050431 [transforming growth factor beta binding]
GO:0050892 [intestinal absorption]
GO:0050909 [sensory perception of taste]
GO:0070053 [thrombospondin receptor activity]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070508 [cholesterol import]
GO:0070542 [response to fatty acid]
GO:0070543 [response to linoleic acid]
GO:0071813 [lipoprotein particle binding]
GO:2000505 [regulation of energy homeostasis]
Show all
472 aa
53.1 kDa
No 2
CD36-202
ENSP00000401863
ENST00000433696
P16671 [Direct mapping]
Platelet glycoprotein 4
Show all
CD markers
Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001954 [positive regulation of cell-matrix adhesion]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0002576 [platelet degranulation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0005041 [low-density lipoprotein receptor activity]
GO:0005615 [extracellular space]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006629 [lipid metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007155 [cell adhesion]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0007263 [nitric oxide mediated signal transduction]
GO:0007596 [blood coagulation]
GO:0008289 [lipid binding]
GO:0009986 [cell surface]
GO:0010744 [positive regulation of macrophage derived foam cell differentiation]
GO:0016020 [membrane]
GO:0019915 [lipid storage]
GO:0019934 [cGMP-mediated signaling]
GO:0030168 [platelet activation]
GO:0030169 [low-density lipoprotein particle binding]
GO:0030299 [intestinal cholesterol absorption]
GO:0030301 [cholesterol transport]
GO:0030666 [endocytic vesicle membrane]
GO:0031092 [platelet alpha granule membrane]
GO:0031526 [brush border membrane]
GO:0033993 [response to lipid]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034197 [triglyceride transport]
GO:0034381 [plasma lipoprotein particle clearance]
GO:0034383 [low-density lipoprotein particle clearance]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042953 [lipoprotein transport]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0044539 [long-chain fatty acid import]
GO:0045087 [innate immune response]
GO:0045335 [phagocytic vesicle]
GO:0050431 [transforming growth factor beta binding]
GO:0050892 [intestinal absorption]
GO:0050909 [sensory perception of taste]
GO:0070053 [thrombospondin receptor activity]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070508 [cholesterol import]
GO:0070542 [response to fatty acid]
GO:0070543 [response to linoleic acid]
GO:0071813 [lipoprotein particle binding]
GO:2000505 [regulation of energy homeostasis]
Show all
433 aa
48.6 kDa
No 2
CD36-203
ENSP00000439543
ENST00000538969
P16671 [Direct mapping]
Platelet glycoprotein 4
Show all
CD markers
Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001954 [positive regulation of cell-matrix adhesion]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0002576 [platelet degranulation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0005041 [low-density lipoprotein receptor activity]
GO:0005615 [extracellular space]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006629 [lipid metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007155 [cell adhesion]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0007263 [nitric oxide mediated signal transduction]
GO:0007596 [blood coagulation]
GO:0008289 [lipid binding]
GO:0009986 [cell surface]
GO:0010744 [positive regulation of macrophage derived foam cell differentiation]
GO:0016020 [membrane]
GO:0019915 [lipid storage]
GO:0019934 [cGMP-mediated signaling]
GO:0030168 [platelet activation]
GO:0030169 [low-density lipoprotein particle binding]
GO:0030299 [intestinal cholesterol absorption]
GO:0030301 [cholesterol transport]
GO:0030666 [endocytic vesicle membrane]
GO:0031092 [platelet alpha granule membrane]
GO:0031526 [brush border membrane]
GO:0033993 [response to lipid]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034197 [triglyceride transport]
GO:0034381 [plasma lipoprotein particle clearance]
GO:0034383 [low-density lipoprotein particle clearance]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042953 [lipoprotein transport]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0044539 [long-chain fatty acid import]
GO:0045087 [innate immune response]
GO:0045335 [phagocytic vesicle]
GO:0050431 [transforming growth factor beta binding]
GO:0050892 [intestinal absorption]
GO:0050909 [sensory perception of taste]
GO:0070053 [thrombospondin receptor activity]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070508 [cholesterol import]
GO:0070542 [response to fatty acid]
GO:0070543 [response to linoleic acid]
GO:0071813 [lipoprotein particle binding]
GO:2000505 [regulation of energy homeostasis]
Show all
412 aa
46.1 kDa
No 2
CD36-204
ENSP00000441956
ENST00000544133
P16671 [Direct mapping]
Platelet glycoprotein 4
Show all
CD markers
Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Potential drug targets
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001954 [positive regulation of cell-matrix adhesion]
GO:0002224 [toll-like receptor signaling pathway]
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I]
GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent]
GO:0002576 [platelet degranulation]
GO:0002755 [MyD88-dependent toll-like receptor signaling pathway]
GO:0005041 [low-density lipoprotein receptor activity]
GO:0005615 [extracellular space]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006629 [lipid metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007155 [cell adhesion]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0007263 [nitric oxide mediated signal transduction]
GO:0007596 [blood coagulation]
GO:0008289 [lipid binding]
GO:0009986 [cell surface]
GO:0010744 [positive regulation of macrophage derived foam cell differentiation]
GO:0016020 [membrane]
GO:0019915 [lipid storage]
GO:0019934 [cGMP-mediated signaling]
GO:0030168 [platelet activation]
GO:0030169 [low-density lipoprotein particle binding]
GO:0030299 [intestinal cholesterol absorption]
GO:0030301 [cholesterol transport]
GO:0030666 [endocytic vesicle membrane]
GO:0031092 [platelet alpha granule membrane]
GO:0031526 [brush border membrane]
GO:0033993 [response to lipid]
GO:0034134 [toll-like receptor 2 signaling pathway]
GO:0034142 [toll-like receptor 4 signaling pathway]
GO:0034197 [triglyceride transport]
GO:0034381 [plasma lipoprotein particle clearance]
GO:0034383 [low-density lipoprotein particle clearance]
GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway]
GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway]
GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I]
GO:0042953 [lipoprotein transport]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0044539 [long-chain fatty acid import]
GO:0045087 [innate immune response]
GO:0045335 [phagocytic vesicle]
GO:0050431 [transforming growth factor beta binding]
GO:0050892 [intestinal absorption]
GO:0050909 [sensory perception of taste]
GO:0070053 [thrombospondin receptor activity]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0070508 [cholesterol import]
GO:0070542 [response to fatty acid]
GO:0070543 [response to linoleic acid]
GO:0071813 [lipoprotein particle binding]
GO:2000505 [regulation of energy homeostasis]
Show all
288 aa
32.3 kDa
No 1

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