Expression of FAIM2 in cancer - Summary - The Human Protein Atlas

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FAIM2

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TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Fas apoptotic inhibitory molecule 2

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA018790	HPA048800

GENE INFORMATION
Gene name	FAIM2 (HGNC Symbol)
Synonyms	KIAA0950, LFG, LFG2, LIFEGUARD, NMP35, TMBIM2
Description	Fas apoptotic inhibitory molecule 2 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q13.12
Chromosome location (bp)	49866896 - 49904217
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000135472 (version 83.38)
Entrez gene	23017
UniProt	Q9BWQ8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BWQ8
Antibodypedia	FAIM2 antibodies

PROTEIN BROWSER

FAIM2-001	FAIM2-002	FAIM2-003	FAIM2-005	FAIM2-006	FAIM2-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAIM2-001 ENSP00000321951 ENST00000320634	Q9BWQ8 [Direct mapping] Protein lifeguard 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0002931 [response to ischemia] GO:0006915 [apoptotic process] GO:0016021 [integral component of membrane] GO:0021549 [cerebellum development] GO:0021680 [cerebellar Purkinje cell layer development] GO:0021681 [cerebellar granular layer development] GO:0021702 [cerebellar Purkinje cell differentiation] GO:0030054 [cell junction] GO:0043066 [negative regulation of apoptotic process] GO:0043523 [regulation of neuron apoptotic process] GO:0043524 [negative regulation of neuron apoptotic process] GO:0045121 [membrane raft] GO:0045211 [postsynaptic membrane] GO:2001234 [negative regulation of apoptotic signaling pathway] Show all	316 aa 35.1 kDa	No	7
FAIM2-002 ENSP00000450132 ENST00000550890	Q9BWQ8 [Direct mapping] Protein lifeguard 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0006915 [apoptotic process] GO:0016021 [integral component of membrane] GO:0021549 [cerebellum development] GO:0021680 [cerebellar Purkinje cell layer development] GO:0021681 [cerebellar granular layer development] GO:0021702 [cerebellar Purkinje cell differentiation] GO:0030054 [cell junction] GO:0043066 [negative regulation of apoptotic process] GO:0043523 [regulation of neuron apoptotic process] GO:0045121 [membrane raft] GO:0045211 [postsynaptic membrane] Show all	270 aa 30.4 kDa	No	7
FAIM2-003 ENSP00000446771 ENST00000552669	F8W1L3 [Direct mapping] Protein lifeguard 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	266 aa 30.4 kDa	No	7
FAIM2-005 ENSP00000449957 ENST00000552863	H0YIR3 [Direct mapping] Protein lifeguard 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	145 aa 16.3 kDa	No	4
FAIM2-006 ENSP00000449711 ENST00000550635	A0A0A0MTP9 [Direct mapping] Protein lifeguard 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	248 aa 27.3 kDa	No	5
FAIM2-007 ENSP00000449360 ENST00000547871	F8VV65 [Direct mapping] Protein lifeguard 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	111 aa 12.5 kDa	No	2

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.