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CKAP2

CANCER ATLAS

Gene description

 Cytoskeleton associated protein 2

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA008410
HPA027821

GENE INFORMATION

Gene name

 CKAP2 (HGNC Symbol)

Synonyms

 FLJ10749, LB1, se20-10, TMAP

Description

 Cytoskeleton associated protein 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a cytoskeleton-associated protein that stabalizes microtubules and plays a role in the regulation of cell division. The encoded protein is itself regulated through phosphorylation at multiple serine and threonine residues. There is a pseudogene of this gene on chromosome 14. Alternative splicing results in multiple transcript variations. [provided by RefSeq, Nov 2013]

Chromosome

 13

Cytoband

 q14.3

Chromosome location (bp)

 52455429 - 52476628

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000136108 (version 83.38)

Entrez gene

 26586

UniProt

 Q8WWK9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8WWK9

Antibodypedia

 CKAP2 antibodies

PROTEIN BROWSER
CKAP2-001
CKAP2-002
CKAP2-003
CKAP2-004
CKAP2-005
CKAP2-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CKAP2-001
ENSP00000258607
ENST00000258607
Q8WWK9 [Direct mapping]
Cytoskeleton-associated protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000281 [mitotic cytokinesis]
GO:0000922 [spindle pole]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005881 [cytoplasmic microtubule]
GO:0006915 [apoptotic process]
GO:0015630 [microtubule cytoskeleton]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
Show all
 682 aa
76.9 kDa 		No 0
CKAP2-002
ENSP00000367273
ENST00000378034
Q8WWK9 [Direct mapping]
Cytoskeleton-associated protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000281 [mitotic cytokinesis]
GO:0000922 [spindle pole]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005881 [cytoplasmic microtubule]
GO:0006915 [apoptotic process]
GO:0015630 [microtubule cytoskeleton]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
Show all
 494 aa
55.3 kDa 		No 0
CKAP2-003
ENSP00000367276
ENST00000378037
Q8WWK9 [Direct mapping]
Cytoskeleton-associated protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000281 [mitotic cytokinesis]
GO:0000922 [spindle pole]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005881 [cytoplasmic microtubule]
GO:0006915 [apoptotic process]
GO:0007026 [negative regulation of microtubule depolymerization]
GO:0015630 [microtubule cytoskeleton]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
Show all
 683 aa
77 kDa 		No 0
CKAP2-004
ENSP00000417830
ENST00000490903
Q8WWK9 [Direct mapping]
Cytoskeleton-associated protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000281 [mitotic cytokinesis]
GO:0000922 [spindle pole]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005881 [cytoplasmic microtubule]
GO:0006915 [apoptotic process]
GO:0015630 [microtubule cytoskeleton]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
Show all
 634 aa
71.2 kDa 		No 0
CKAP2-005
ENSP00000418224
ENST00000480747
C9J7Y4 [Direct mapping]
Cytoskeleton-associated protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 97 aa
10.9 kDa 		No 0
CKAP2-006
ENSP00000418431
ENST00000468284
C9J649 [Direct mapping]
Cytoskeleton-associated protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 94 aa
10.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.