Expression of ZFHX2 in cancer - Summary

CANCER ATLAS

Gene description

Zinc finger homeobox 2

Protein class

Plasma proteins, Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Stomach cancer

STAINING SUMMARY

HPA000720	HPA005146

GENE INFORMATION
Gene name	ZFHX2 (HGNC Symbol)
Synonyms	KIAA1056, KIAA1762, ZFH-5, ZNF409
Description	Zinc finger homeobox 2 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	23520855 - 23556192
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136367 (version 83.38)
Entrez gene	85446
UniProt	Q9C0A1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9C0A1
Antibodypedia	ZFHX2 antibodies

PROTEIN BROWSER

ZFHX2-001	ZFHX2-004	ZFHX2-005	ZFHX2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZFHX2-001 ENSP00000413418 ENST00000419474	Q9C0A1 [Direct mapping] Zinc finger homeobox protein 2 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Transcription factors Helix-turn-helix domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0030534 [adult behavior] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] Show all	2572 aa 274.2 kDa	No	0
ZFHX2-004 ENSP00000409464 ENST00000412565	C9JSX6 [Direct mapping] Zinc finger homeobox protein 2 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0046872 [metal ion binding] Show all	361 aa 37.9 kDa	No	0
ZFHX2-005 ENSP00000451342 ENST00000555334	G3V3N5 [Direct mapping] Zinc finger homeobox protein 2 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		246 aa 25.8 kDa	No	0
ZFHX2-201 ENSP00000478696 ENST00000615307	A2RRC6 [Direct mapping] ZFHX2 protein; Zinc finger homeobox protein 2 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0046872 [metal ion binding] Show all	408 aa 43.2 kDa	No	0