Tissue expression of CD72 - Summary - The Human Protein Atlas

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CD72

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TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CD72
Gene description	CD72 molecule
Protein class	CD markers Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (lymph node, spleen, tonsil, appendix)
GTEx:	Tissue enriched (spleen)
FANTOM5:	Tissue enhanced (spleen, tonsil)

Protein evidence

Evidence at protein level

Protein expression

Selective membranous expression in lymphocytes.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA044658 , CAB002505
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (lymph node, spleen, tonsil, appendix)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (spleen)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (spleen, tonsil)

GENE INFORMATION
Gene name	CD72 (HGNC Symbol)
Synonyms	CD72b, LYB2
Description	CD72 molecule (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	p13.3
Chromosome location (bp)	35609533 - 35646810
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000137101 (version 83.38)
Entrez gene	971
UniProt	P21854 (UniProt - Evidence at transcript level)
neXtProt	NX_P21854
Antibodypedia	CD72 antibodies

PROTEIN BROWSER

CD72-001	CD72-005	CD72-009	CD72-201	CD72-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CD72-001 ENSP00000379980 ENST00000396757	P21854 [Direct mapping] B-cell differentiation antigen CD72 Q5TLG3 [Target identity:100%; Query identity:100%] CD72 antigen; CD72 antigen, isoform CRA_a; CD72 molecule Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004888 [transmembrane signaling receptor activity] GO:0005102 [receptor binding] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007155 [cell adhesion] GO:0007165 [signal transduction] GO:0007411 [axon guidance] GO:0030246 [carbohydrate binding] Show all	359 aa 40.2 kDa	No	1
CD72-005 ENSP00000367687 ENST00000378430	Q5T4Q7 [Direct mapping] B-cell differentiation antigen CD72 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		120 aa 12.2 kDa	No	0
CD72-009 ENSP00000367688 ENST00000378431	Q5T4Q8 [Direct mapping] B-cell differentiation antigen CD72 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	119 aa 12.5 kDa	No	1
CD72-201 ENSP00000259633 ENST00000259633	P21854 [Direct mapping] B-cell differentiation antigen CD72 Q5TLG3 [Target identity:100%; Query identity:100%] CD72 antigen; CD72 antigen, isoform CRA_a; CD72 molecule Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004888 [transmembrane signaling receptor activity] GO:0005102 [receptor binding] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007155 [cell adhesion] GO:0007165 [signal transduction] GO:0007411 [axon guidance] GO:0030246 [carbohydrate binding] Show all	359 aa 40.2 kDa	No	1
CD72-202 ENSP00000483742 ENST00000612238	A0A087X0Y7 [Direct mapping] B-cell differentiation antigen CD72 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	359 aa 40.1 kDa	No	1

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.