We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Several liver, testicular, urothelial, gastric, renal, pancreatic, prostate, endometrial and colorectal cancers showed moderate to strong cytoplasmic positivity. Remaining malignancies were in general weakly stained or negative.
A few cases of hepatocellular carcinomas and renal cancers showed weak to moderate cytoplasmic staining. Remaining cancer cells were weakly stained or negative.
GENE INFORMATION
Gene name
SLC37A4 (HGNC Symbol)
Synonyms
G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d
Description
Solute carrier family 37 (glucose-6-phosphate transporter), member 4 (HGNC Symbol)
Entrez gene summary
This gene regulates glucose-6-phosphate transport from the cytoplasm to the lumen of the endoplasmic reticulum, in order to maintain glucose homeostasis. It also plays a role in ATP-mediated calcium sequestration in the lumen of the endoplasmic reticulum. Mutations in this gene have been associated with various forms of glycogen storage disease. Alternative splicing in this gene results in multiple transcript variants.[provided by RefSeq, Aug 2009]
