Expression of RTF1 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

RTF1 homolog, Paf1/RNA polymerase II complex component

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA006714

GENE INFORMATION
Gene name	RTF1 (HGNC Symbol)
Synonyms	KIAA0252
Description	RTF1 homolog, Paf1/RNA polymerase II complex component (HGNC Symbol)
Entrez gene summary	This locus may represent a gene involved in regulation of transcription elongation and chromatin remodeling, based on studies of similar proteins in other organisms. The encoded protein may bind single-stranded DNA. [provided by RefSeq, Sep 2010]
Chromosome	15
Cytoband	q15.1
Chromosome location (bp)	41408408 - 41483563
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000137815 (version 83.38)
Entrez gene	23168
UniProt	Q92541 (UniProt - Evidence at protein level)
neXtProt	NX_Q92541
Antibodypedia	RTF1 antibodies

PROTEIN BROWSER

RTF1-001	RTF1-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RTF1-001 ENSP00000374280 ENST00000389629	Q92541 [Direct mapping] RNA polymerase-associated protein RTF1 homolog Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001711 [endodermal cell fate commitment] GO:0001832 [blastocyst growth] GO:0003677 [DNA binding] GO:0003697 [single-stranded DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0006352 [DNA-templated transcription, initiation] GO:0006368 [transcription elongation from RNA polymerase II promoter] GO:0016055 [Wnt signaling pathway] GO:0016570 [histone modification] GO:0016593 [Cdc73/Paf1 complex] GO:0019827 [stem cell population maintenance] GO:0032968 [positive regulation of transcription elongation from RNA polymerase II promoter] GO:0044822 [poly(A) RNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0051571 [positive regulation of histone H3-K4 methylation] GO:0080182 [histone H3-K4 trimethylation] Show all	710 aa 80.3 kDa	No	0
RTF1-007 ENSP00000452973 ENST00000560447	H0YKX1 [Direct mapping] RNA polymerase-associated protein RTF1 homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0006368 [transcription elongation from RNA polymerase II promoter] GO:0016570 [histone modification] GO:0016593 [Cdc73/Paf1 complex] Show all	171 aa 20.2 kDa	No	0