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ATRAID

GENERAL INFORMATION

Gene name

 ATRAID

Gene description

 All-trans retinoic acid-induced differentiation factor

Protein class

 Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic or membranous expresusion in selected tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA051353
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 ATRAID (HGNC Symbol)

Synonyms

 APR3, C2orf28, HSPC013, p18

Description

 All-trans retinoic acid-induced differentiation factor (HGNC Symbol)

Entrez gene summary

 This gene is thought to be involved in apoptosis, and may also be involved in hematopoietic development and differentiation. The use of alternative splice sites and promotors result in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2009]

Chromosome

 2

Cytoband

 p23.3

Chromosome location (bp)

 27212027 - 27217178

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000138085 (version 83.38)

Entrez gene

 51374

UniProt

 Q6UW56 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6UW56

Antibodypedia

 ATRAID antibodies

PROTEIN BROWSER
ATRAID-001
ATRAID-002
ATRAID-003
ATRAID-007
ATRAID-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ATRAID-001
ENSP00000369518
ENST00000380171
Q6UW56 [Direct mapping]
All-trans retinoic acid-induced differentiation factor
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005886 [plasma membrane]
GO:0010468 [regulation of gene expression]
GO:0016021 [integral component of membrane]
GO:0030154 [cell differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0033689 [negative regulation of osteoblast proliferation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0048471 [perinuclear region of cytoplasm]
GO:2000599 [negative regulation of cyclin catabolic process]
Show all
 284 aa
30.3 kDa 		No 2
ATRAID-002
ENSP00000384033
ENST00000405489
Q6UW56 [Direct mapping]
All-trans retinoic acid-induced differentiation factor
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005886 [plasma membrane]
GO:0010468 [regulation of gene expression]
GO:0016021 [integral component of membrane]
GO:0030154 [cell differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0033689 [negative regulation of osteoblast proliferation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0048471 [perinuclear region of cytoplasm]
GO:2000599 [negative regulation of cyclin catabolic process]
Show all
 171 aa
18.6 kDa 		No 1
ATRAID-003
ENSP00000397319
ENST00000419744
C9JA62 [Direct mapping]
All-trans retinoic acid-induced differentiation factor
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 75 aa
8.2 kDa 		No 0
ATRAID-007
ENSP00000476080
ENST00000606999
Q6UW56 [Direct mapping]
All-trans retinoic acid-induced differentiation factor
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005886 [plasma membrane]
GO:0010468 [regulation of gene expression]
GO:0016021 [integral component of membrane]
GO:0030154 [cell differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0033689 [negative regulation of osteoblast proliferation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0048471 [perinuclear region of cytoplasm]
GO:2000599 [negative regulation of cyclin catabolic process]
Show all
 229 aa
24.7 kDa 		Yes 1
ATRAID-201
ENSP00000484228
ENST00000611786
Q6UW56 [Direct mapping]
All-trans retinoic acid-induced differentiation factor
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005635 [nuclear envelope]
GO:0005765 [lysosomal membrane]
GO:0005886 [plasma membrane]
GO:0010468 [regulation of gene expression]
GO:0016021 [integral component of membrane]
GO:0030154 [cell differentiation]
GO:0030501 [positive regulation of bone mineralization]
GO:0033689 [negative regulation of osteoblast proliferation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0048471 [perinuclear region of cytoplasm]
GO:2000599 [negative regulation of cyclin catabolic process]
Show all
 284 aa
30.3 kDa 		No 2

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.