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GPAT3

GENERAL INFORMATION

Gene name

 GPAT3

Gene description

 Glycerol-3-phosphate acyltransferase 3

Protein class

 Enzymes
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (kidney)
GTEx:Mixed
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression with a granular pattern.

DATA RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA029414
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (kidney)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 GPAT3 (HGNC Symbol)

Synonyms

 AGPAT10, AGPAT9, HMFN0839, LPAAT-theta, MAG1, MGC11324

Description

 Glycerol-3-phosphate acyltransferase 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the lysophosphatidic acid acyltransferase protein family. The encoded protein is an enzyme which catalyzes the conversion of glycerol-3-phosphate to lysophosphatidic acid in the synthesis of triacylglycerol. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012]

Chromosome

 4

Cytoband

 q21.23

Chromosome location (bp)

 83535914 - 83605875

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000138678 (version 83.38)

Entrez gene

 84803

UniProt

 Q53EU6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q53EU6

Antibodypedia

 GPAT3 antibodies

PROTEIN BROWSER
GPAT3-001
GPAT3-002
GPAT3-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GPAT3-001
ENSP00000378651
ENST00000395226
Q53EU6 [Direct mapping]
Glycerol-3-phosphate acyltransferase 3
A0A024RDG5 [Target identity:100%; Query identity:100%]
Uncharacterized protein
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003841 [1-acylglycerol-3-phosphate O-acyltransferase activity]
GO:0004366 [glycerol-3-phosphate O-acyltransferase activity]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0006644 [phospholipid metabolic process]
GO:0006654 [phosphatidic acid biosynthetic process]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0016024 [CDP-diacylglycerol biosynthetic process]
GO:0016746 [transferase activity, transferring acyl groups]
GO:0019432 [triglyceride biosynthetic process]
GO:0032006 [regulation of TOR signaling]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046474 [glycerophospholipid biosynthetic process]
Show all
 434 aa
48.7 kDa 		No 2
GPAT3-002
ENSP00000264409
ENST00000264409
Q53EU6 [Direct mapping]
Glycerol-3-phosphate acyltransferase 3
A0A024RDG5 [Target identity:100%; Query identity:100%]
Uncharacterized protein
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003841 [1-acylglycerol-3-phosphate O-acyltransferase activity]
GO:0004366 [glycerol-3-phosphate O-acyltransferase activity]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0006644 [phospholipid metabolic process]
GO:0006654 [phosphatidic acid biosynthetic process]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0016024 [CDP-diacylglycerol biosynthetic process]
GO:0016746 [transferase activity, transferring acyl groups]
GO:0019432 [triglyceride biosynthetic process]
GO:0032006 [regulation of TOR signaling]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046474 [glycerophospholipid biosynthetic process]
Show all
 434 aa
48.7 kDa 		No 2
GPAT3-201
ENSP00000482571
ENST00000611707
Q53EU6 [Direct mapping]
Glycerol-3-phosphate acyltransferase 3
A0A024RDG5 [Target identity:100%; Query identity:100%]
Uncharacterized protein
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003841 [1-acylglycerol-3-phosphate O-acyltransferase activity]
GO:0004366 [glycerol-3-phosphate O-acyltransferase activity]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0006644 [phospholipid metabolic process]
GO:0006654 [phosphatidic acid biosynthetic process]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0016024 [CDP-diacylglycerol biosynthetic process]
GO:0016746 [transferase activity, transferring acyl groups]
GO:0019432 [triglyceride biosynthetic process]
GO:0032006 [regulation of TOR signaling]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046474 [glycerophospholipid biosynthetic process]
Show all
 434 aa
48.7 kDa 		No 2

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.