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Prostate, glioma, carcinoids and cases of testis cancer showed moderate to strong cytoplasmic positivity. Remaining tumour cells were negative.
GENE INFORMATION
Gene name
RTN1 (HGNC Symbol)
Synonyms
NSP
Description
Reticulon 1 (HGNC Symbol)
Entrez gene summary
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]
