Expression of ABHD2 in cancer - Summary - The Human Protein Atlas

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ABHD2

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Abhydrolase domain containing 2

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA005999

GENE INFORMATION
Gene name	ABHD2 (HGNC Symbol)
Synonyms	LABH2
Description	Abhydrolase domain containing 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Chromosome	15
Cytoband	q26.1
Chromosome location (bp)	89087459 - 89202360
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000140526 (version 83.38)
Entrez gene	11057
UniProt	P08910 (UniProt - Evidence at transcript level)
neXtProt	NX_P08910
Antibodypedia	ABHD2 antibodies

PROTEIN BROWSER

ABHD2-001	ABHD2-002	ABHD2-005	ABHD2-006	ABHD2-007	ABHD2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABHD2-001 ENSP00000268129 ENST00000352732	P08910 [Direct mapping] Abhydrolase domain-containing protein 2 A0A024RC89 [Target identity:100%; Query identity:100%] Abhydrolase domain containing 2, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0009611 [response to wounding] GO:0016021 [integral component of membrane] GO:0030336 [negative regulation of cell migration] GO:0052689 [carboxylic ester hydrolase activity] Show all	425 aa 48.3 kDa	No	1
ABHD2-002 ENSP00000457882 ENST00000569411	H3BUZ6 [Direct mapping] Abhydrolase domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		131 aa 14.4 kDa	No	1
ABHD2-005 ENSP00000454645 ENST00000569550	H3BN19 [Direct mapping] Abhydrolase domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		56 aa 6.1 kDa	No	1
ABHD2-006 ENSP00000454531 ENST00000565066	H3BMT2 [Direct mapping] Abhydrolase domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		123 aa 13.5 kDa	No	1
ABHD2-007 ENSP00000455639 ENST00000565973	P08910 [Direct mapping] Abhydrolase domain-containing protein 2 A0A024RC89 [Target identity:100%; Query identity:100%] Abhydrolase domain containing 2, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0052689 [carboxylic ester hydrolase activity] Show all	425 aa 48.3 kDa	No	1
ABHD2-201 ENSP00000347217 ENST00000355100	P08910 [Direct mapping] Abhydrolase domain-containing protein 2 A0A024RC89 [Target identity:100%; Query identity:100%] Abhydrolase domain containing 2, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0052689 [carboxylic ester hydrolase activity] Show all	425 aa 48.3 kDa	No	1

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.