Tissue expression of ABHD2 - Summary - The Human Protein Atlas

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ABHD2

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ABHD2
Gene description	Abhydrolase domain containing 2
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic and nuclear expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA005999
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ABHD2 (HGNC Symbol)
Synonyms	LABH2
Description	Abhydrolase domain containing 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Chromosome	15
Cytoband	q26.1
Chromosome location (bp)	89087459 - 89202360
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000140526 (version 83.38)
Entrez gene	11057
UniProt	P08910 (UniProt - Evidence at transcript level)
neXtProt	NX_P08910
Antibodypedia	ABHD2 antibodies

PROTEIN BROWSER

ABHD2-001	ABHD2-002	ABHD2-005	ABHD2-006	ABHD2-007	ABHD2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABHD2-001 ENSP00000268129 ENST00000352732	P08910 [Direct mapping] Abhydrolase domain-containing protein 2 A0A024RC89 [Target identity:100%; Query identity:100%] Abhydrolase domain containing 2, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0009611 [response to wounding] GO:0016021 [integral component of membrane] GO:0030336 [negative regulation of cell migration] GO:0052689 [carboxylic ester hydrolase activity] Show all	425 aa 48.3 kDa	No	1
ABHD2-002 ENSP00000457882 ENST00000569411	H3BUZ6 [Direct mapping] Abhydrolase domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		131 aa 14.4 kDa	No	1
ABHD2-005 ENSP00000454645 ENST00000569550	H3BN19 [Direct mapping] Abhydrolase domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		56 aa 6.1 kDa	No	1
ABHD2-006 ENSP00000454531 ENST00000565066	H3BMT2 [Direct mapping] Abhydrolase domain-containing protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		123 aa 13.5 kDa	No	1
ABHD2-007 ENSP00000455639 ENST00000565973	P08910 [Direct mapping] Abhydrolase domain-containing protein 2 A0A024RC89 [Target identity:100%; Query identity:100%] Abhydrolase domain containing 2, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0052689 [carboxylic ester hydrolase activity] Show all	425 aa 48.3 kDa	No	1
ABHD2-201 ENSP00000347217 ENST00000355100	P08910 [Direct mapping] Abhydrolase domain-containing protein 2 A0A024RC89 [Target identity:100%; Query identity:100%] Abhydrolase domain containing 2, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0008150 [biological_process] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0052689 [carboxylic ester hydrolase activity] Show all	425 aa 48.3 kDa	No	1

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.