Expression of ARSG in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Arylsulfatase G

Protein class

Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA023245	HPA023285

GENE INFORMATION
Gene name	ARSG (HGNC Symbol)
Synonyms	KIAA1001
Description	Arylsulfatase G (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
Chromosome	17
Cytoband	q24.2
Chromosome location (bp)	68259182 - 68422731
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000141337 (version 83.38)
Entrez gene	22901
UniProt	Q96EG1 (UniProt - Evidence at protein level)
neXtProt	NX_Q96EG1
Antibodypedia	ARSG antibodies

PROTEIN BROWSER

ARSG-002	ARSG-003	ARSG-004	ARSG-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARSG-002 ENSP00000407193 ENST00000448504	Q96EG1 [Direct mapping] Arylsulfatase G A0A024R8K1 [Target identity:100%; Query identity:100%] Arylsulfatase G, isoform CRA_a Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004065 [arylsulfatase activity] GO:0005615 [extracellular space] GO:0005764 [lysosome] GO:0005783 [endoplasmic reticulum] GO:0005788 [endoplasmic reticulum lumen] GO:0006665 [sphingolipid metabolic process] GO:0006687 [glycosphingolipid metabolic process] GO:0006790 [sulfur compound metabolic process] GO:0008152 [metabolic process] GO:0008484 [sulfuric ester hydrolase activity] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] Show all	525 aa 57.1 kDa	Yes	0
ARSG-003 ENSP00000413953 ENST00000452479	J9JIG6 [Direct mapping] Arylsulfatase G Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] GO:0008484 [sulfuric ester hydrolase activity] Show all	361 aa 39.2 kDa	No	0
ARSG-004 ENSP00000462306 ENST00000581639	J3KS49 [Direct mapping] Arylsulfatase G Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		29 aa 3.2 kDa	Yes	0
ARSG-201 ENSP00000480910 ENST00000621439	Q96EG1 [Direct mapping] Arylsulfatase G A0A024R8K1 [Target identity:100%; Query identity:100%] Arylsulfatase G, isoform CRA_a Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004065 [arylsulfatase activity] GO:0005615 [extracellular space] GO:0005764 [lysosome] GO:0005783 [endoplasmic reticulum] GO:0005788 [endoplasmic reticulum lumen] GO:0006665 [sphingolipid metabolic process] GO:0006687 [glycosphingolipid metabolic process] GO:0006790 [sulfur compound metabolic process] GO:0008152 [metabolic process] GO:0008484 [sulfuric ester hydrolase activity] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] Show all	525 aa 57.1 kDa	Yes	0