Expression of ESCO1 in cancer - Summary

CANCER ATLAS

Gene description

Establishment of sister chromatid cohesion N-acetyltransferase 1

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA042497

GENE INFORMATION
Gene name	ESCO1 (HGNC Symbol)
Synonyms	EFO1, ESO1, KIAA1911
Description	Establishment of sister chromatid cohesion N-acetyltransferase 1 (HGNC Symbol)
Entrez gene summary	ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion (Hou and Zou, 2005 [PubMed 15958495]).[supplied by OMIM, Mar 2008]
Chromosome	18
Cytoband	q11.2
Chromosome location (bp)	21529281 - 21600884
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000141446 (version 83.38)
Entrez gene	114799
UniProt	Q5FWF5 (UniProt - Evidence at protein level)
neXtProt	NX_Q5FWF5
Antibodypedia	ESCO1 antibodies

PROTEIN BROWSER

ESCO1-001	ESCO1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ESCO1-001 ENSP00000269214 ENST00000269214	Q5FWF5 [Direct mapping] N-acetyltransferase ESCO1 A0A024RC19 [Target identity:100%; Query identity:100%] Establishment of cohesion 1 homolog 1 (S. cerevisiae), isoform CRA_b Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000278 [mitotic cell cycle] GO:0000785 [chromatin] GO:0005654 [nucleoplasm] GO:0006275 [regulation of DNA replication] GO:0007062 [sister chromatid cohesion] GO:0016746 [transferase activity, transferring acyl groups] GO:0034421 [post-translational protein acetylation] GO:0046872 [metal ion binding] Show all	840 aa 95 kDa	No	0
ESCO1-201 ENSP00000484873 ENST00000622333	A0A0C4DH04 [Direct mapping] N-acetyltransferase ESCO1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000785 [chromatin] GO:0006275 [regulation of DNA replication] GO:0007062 [sister chromatid cohesion] GO:0034421 [post-translational protein acetylation] Show all	172 aa 19.9 kDa	No	0