Expression of NT5C3B in cancer - Summary

CANCER ATLAS

Gene description

5'-nucleotidase, cytosolic IIIB

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA030786	HPA057095

GENE INFORMATION
Gene name	NT5C3B (HGNC Symbol)
Synonyms	MGC20781, NT5C3L
Description	5'-nucleotidase, cytosolic IIIB (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q21.2
Chromosome location (bp)	41825181 - 41836263
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000141698 (version 83.38)
Entrez gene	115024
UniProt	Q969T7 (UniProt - Evidence at protein level)
neXtProt	NX_Q969T7
Antibodypedia	NT5C3B antibodies

PROTEIN BROWSER

NT5C3B-008	NT5C3B-009	NT5C3B-013	NT5C3B-017

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NT5C3B-008 ENSP00000389948 ENST00000435506	Q969T7 [Direct mapping] 7-methylguanosine phosphate-specific 5'-nucleotidase Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0008253 [5'-nucleotidase activity] GO:0009117 [nucleotide metabolic process] GO:0010467 [gene expression] GO:0016311 [dephosphorylation] GO:0043928 [exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay] Show all	300 aa 34.4 kDa	No	0
NT5C3B-009 ENSP00000397742 ENST00000415460	C9J758 [Direct mapping] 7-methylguanosine phosphate-specific 5'-nucleotidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0005737 [cytoplasm] GO:0008253 [5'-nucleotidase activity] GO:0016311 [dephosphorylation] Show all	227 aa 25.8 kDa	No	0
NT5C3B-013 ENSP00000475710 ENST00000486304	U3KQB1 [Direct mapping] 7-methylguanosine phosphate-specific 5'-nucleotidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0005737 [cytoplasm] GO:0008253 [5'-nucleotidase activity] GO:0016311 [dephosphorylation] Show all	105 aa 12 kDa	No	0
NT5C3B-017 ENSP00000429878 ENST00000521789	E5RH64 [Direct mapping] 7-methylguanosine phosphate-specific 5'-nucleotidase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0005737 [cytoplasm] GO:0008253 [5'-nucleotidase activity] GO:0016311 [dephosphorylation] Show all	200 aa 23.6 kDa	No	0