Cell atlas - PROK1 - The Human Protein Atlas

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PROK1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	PROK1
Gene description	Prokineticin 1
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	PROK1 (HGNC Symbol)
Synonyms	EGVEGF, PK1, PRK1
Description	Prokineticin 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner. [provided by RefSeq, Sep 2011]
Chromosome	1
Cytoband	p13.3
Chromosome location (bp)	110451200 - 110457354
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143125 (version 83.38)
Entrez gene	84432
UniProt	P58294 (UniProt - Evidence at protein level)
neXtProt	NX_P58294
Antibodypedia	PROK1 antibodies

PROTEIN BROWSER

PROK1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PROK1-001 ENSP00000271331 ENST00000271331	P58294 [Direct mapping] Prokineticin-1 A0A024R0B1 [Target identity:100%; Query identity:100%] Prokineticin 1, isoform CRA_a Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0000187 [activation of MAPK activity] GO:0001525 [angiogenesis] GO:0001664 [G-protein coupled receptor binding] GO:0005576 [extracellular region] GO:0007623 [circadian rhythm] GO:0008083 [growth factor activity] GO:0008284 [positive regulation of cell proliferation] GO:0045765 [regulation of angiogenesis] GO:0051781 [positive regulation of cell division] Show all	105 aa 11.7 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.