Expression of TOR1AIP1 in cancer - Summary

CANCER ATLAS

Gene description

Torsin A interacting protein 1

Protein class

Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA047151	HPA050546

GENE INFORMATION
Gene name	TOR1AIP1 (HGNC Symbol)
Synonyms	FLJ13142, LAP1B
Description	Torsin A interacting protein 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a type 2 integral membrane protein that binds A- and B-type laminins. The encoded protein localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Chromosome	1
Cytoband	q25.2
Chromosome location (bp)	179882042 - 179925000
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143337 (version 83.38)
Entrez gene	26092
UniProt	Q5JTV8 (UniProt - Evidence at protein level)
neXtProt	NX_Q5JTV8
Antibodypedia	TOR1AIP1 antibodies

PROTEIN BROWSER

TOR1AIP1-001	TOR1AIP1-002	TOR1AIP1-004	TOR1AIP1-008	TOR1AIP1-011	TOR1AIP1-012	TOR1AIP1-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TOR1AIP1-001 ENSP00000435365 ENST00000528443	Q5JTV8 [Direct mapping] Torsin-1A-interacting protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001671 [ATPase activator activity] GO:0005515 [protein binding] GO:0005521 [lamin binding] GO:0005634 [nucleus] GO:0005635 [nuclear envelope] GO:0005637 [nuclear inner membrane] GO:0008092 [cytoskeletal protein binding] GO:0016021 [integral component of membrane] GO:0032781 [positive regulation of ATPase activity] GO:0034504 [protein localization to nucleus] GO:0051117 [ATPase binding] GO:0071763 [nuclear membrane organization] Show all	584 aa 66.3 kDa	No	1
TOR1AIP1-002 ENSP00000393613 ENST00000447964	H0Y4R4 [Direct mapping] Torsin-1A-interacting protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	296 aa 33.6 kDa	No	1
TOR1AIP1-004 ENSP00000476687 ENST00000606911	Q5JTV8 [Direct mapping] Torsin-1A-interacting protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001671 [ATPase activator activity] GO:0005634 [nucleus] GO:0005637 [nuclear inner membrane] GO:0008092 [cytoskeletal protein binding] GO:0016021 [integral component of membrane] GO:0032781 [positive regulation of ATPase activity] GO:0034504 [protein localization to nucleus] GO:0051117 [ATPase binding] Show all	583 aa 66.2 kDa	No	1
TOR1AIP1-008 ENSP00000434316 ENST00000531630	H0YDU3 [Direct mapping] Torsin-1A-interacting protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		193 aa 22.4 kDa	No	0
TOR1AIP1-011 ENSP00000271583 ENST00000271583	J3KN66 [Direct mapping] Torsin-1A-interacting protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		599 aa 67.8 kDa	No	1
TOR1AIP1-012 ENSP00000432717 ENST00000527391	H0YD16 [Direct mapping] Torsin-1A-interacting protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		198 aa 22.2 kDa	No	0
TOR1AIP1-015 ENSP00000393292 ENST00000435319	A0A0A0MSK5 [Direct mapping] Torsin-1A-interacting protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	462 aa 52.4 kDa	No	1