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Most cancer tissues showed weak to moderate cytoplasmic positivity combined with cases of nuclear staining. Cases of high grade gliomas displayed strong cytoplasmic immunoreactivity while lymphomas were negative.
Cancer tissues displayed weak to moderate cytoplasmic staining with additional membranous positivity in several cases. Few cases of gliomas, thyroid, prostate, pancreatic, breast and renal cancers were strongly positive. Majority of the cases of lymphomas were negative.
GENE INFORMATION
Gene name
TUFT1
Synonyms
Description
Tuftelin 1 (HGNC Symbol)
Entrez gene summary
Tuftelin is an acidic protein that is thought to play a role in dental enamel mineralization and is implicated in caries susceptibility. It is also thought to be involved with adaptation to hypoxia, mesenchymal stem cell function, and neurotrophin nerve growth factor mediated neuronal differentiation. [provided by RefSeq, Aug 2014]
