Expression of SFXN5 in cancer - Summary

CANCER ATLAS

Gene description

Sideroflexin 5

Protein class

Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA015473

GENE INFORMATION
Gene name	SFXN5 (HGNC Symbol)
Synonyms	BBG-TCC
Description	Sideroflexin 5 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p13.2
Chromosome location (bp)	72942036 - 73075619
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000144040 (version 83.38)
Entrez gene	94097
UniProt	Q8TD22 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TD22
Antibodypedia	SFXN5 antibodies

PROTEIN BROWSER

SFXN5-001	SFXN5-002	SFXN5-003	SFXN5-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SFXN5-001 ENSP00000272433 ENST00000272433	Q8TD22 [Direct mapping] Sideroflexin-5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0006811 [ion transport] GO:0015075 [ion transmembrane transporter activity] GO:0015137 [citrate transmembrane transporter activity] GO:0015746 [citrate transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0055072 [iron ion homeostasis] GO:0055085 [transmembrane transport] Show all	340 aa 37.1 kDa	Yes	5
SFXN5-002 ENSP00000387076 ENST00000410065	B8ZZJ6 [Direct mapping] Sideroflexin-5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006811 [ion transport] GO:0015075 [ion transmembrane transporter activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] Show all	253 aa 28 kDa	Yes	1
SFXN5-003 ENSP00000402141 ENST00000411783	H7C1S9 [Direct mapping] Sideroflexin-5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006811 [ion transport] GO:0015075 [ion transmembrane transporter activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] Show all	252 aa 27.4 kDa	No	2
SFXN5-011 ENSP00000396825 ENST00000442582	C9JIV5 [Direct mapping] Sideroflexin-5 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006811 [ion transport] GO:0015075 [ion transmembrane transporter activity] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] Show all	156 aa 17.2 kDa	Yes	0