Cell atlas - LIPT1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

LIPT1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	LIPT1
Gene description	Lipoyltransferase 1
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	LIPT1 (HGNC Symbol)
Synonyms	MGC12290, MGC13378
Description	Lipoyltransferase 1 (HGNC Symbol)
Entrez gene summary	The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 13. Read-through transcription also exists between this gene and the neighboring downstream mitochondrial ribosomal protein L30 (MRPL30) gene. [provided by RefSeq, Mar 2011]
Chromosome	2
Cytoband	q11.2
Chromosome location (bp)	99154955 - 99163157
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000144182 (version 83.38)
Entrez gene	51601
UniProt	Q9Y234 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y234
Antibodypedia	LIPT1 antibodies

PROTEIN BROWSER

LIPT1-001	LIPT1-002	LIPT1-003	LIPT1-005	LIPT1-006	LIPT1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LIPT1-001 ENSP00000377115 ENST00000393473	Q9Y234 [Direct mapping] Lipoyltransferase 1, mitochondrial Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006464 [cellular protein modification process] GO:0006629 [lipid metabolic process] GO:0009249 [protein lipoylation] GO:0016746 [transferase activity, transferring acyl groups] Show all	373 aa 42.5 kDa	No	0
LIPT1-002 ENSP00000387387 ENST00000449211	C9JW10 [Direct mapping] Lipoyltransferase 1, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006464 [cellular protein modification process] Show all	135 aa 15.7 kDa	No	0
LIPT1-003 ENSP00000393591 ENST00000434566	C9JUU5 [Direct mapping] Lipoyltransferase 1, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006464 [cellular protein modification process] Show all	251 aa 28.3 kDa	No	0
LIPT1-005 ENSP00000398168 ENST00000415142	C9J6A9 [Direct mapping] Lipoyltransferase 1, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006464 [cellular protein modification process] Show all	106 aa 12.1 kDa	No	0
LIPT1-006 ENSP00000406314 ENST00000436234	C9J7C5 [Direct mapping] Lipoyltransferase 1, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		39 aa 4.3 kDa	No	0
LIPT1-201 ENSP00000377114 ENST00000393471	Q9Y234 [Direct mapping] Lipoyltransferase 1, mitochondrial Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006464 [cellular protein modification process] GO:0006629 [lipid metabolic process] GO:0009249 [protein lipoylation] GO:0016746 [transferase activity, transferring acyl groups] Show all	373 aa 42.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.