Expression of UBXN4 in cancer - Summary

CANCER ATLAS

Gene description

UBX domain protein 4

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA036325

GENE INFORMATION
Gene name	UBXN4 (HGNC Symbol)
Synonyms	KIAA0242, UBXD2, UBXDC1
Description	UBX domain protein 4 (HGNC Symbol)
Entrez gene summary	UBXD2 is an integral membrane protein of the endoplasmic reticulum (ER) that binds valosin-containing protein (VCP; MIM 601023) and promotes ER-associated protein degradation (ERAD) (Liang et al., 2006 [PubMed 16968747]).[supplied by OMIM, Mar 2008]
Chromosome	2
Cytoband	q21.3
Chromosome location (bp)	135741619 - 135785055
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000144224 (version 83.38)
Entrez gene	23190
UniProt	Q92575 (UniProt - Evidence at protein level)
neXtProt	NX_Q92575
Antibodypedia	UBXN4 antibodies

PROTEIN BROWSER

UBXN4-001	UBXN4-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UBXN4-001 ENSP00000272638 ENST00000272638	Q92575 [Direct mapping] UBX domain-containing protein 4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005635 [nuclear envelope] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006986 [response to unfolded protein] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] Show all	508 aa 56.8 kDa	No	1
UBXN4-004 ENSP00000401748 ENST00000415164	C9JLR4 [Direct mapping] UBX domain-containing protein 4 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		117 aa 12.3 kDa	No	0