Cell atlas - NICN1 - The Human Protein Atlas

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NICN1

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	NICN1
Gene description	Nicolin 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA058014
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA058014	HeLa	Nucleoplasm
	HPA058014	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	NICN1 (HGNC Symbol)
Synonyms	MGC12936
Description	Nicolin 1 (HGNC Symbol)
Entrez gene summary	This protein encoded by this gene localizes to the nucleus and is expressed in numerous tissues including brain, testis, liver, and kidney. This refseq contains genomic sequence in its 3' UTR which is not supported by experimental evidence. Computer predictions indicate that this region of the 3' UTR contains hairpin-forming self-complementary sequence which is possibly excised after transcription. This gene has a pseudogene on chromosome X. [provided by RefSeq, Jul 2008]
Chromosome	3
Cytoband	p21.31
Chromosome location (bp)	49422946 - 49429326
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000145029 (version 83.38)
Entrez gene	84276
UniProt	Q9BSH3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BSH3
Antibodypedia	NICN1 antibodies

PROTEIN BROWSER

NICN1-002	NICN1-006	NICN1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NICN1-002 ENSP00000273598 ENST00000273598	Q9BSH3 [Direct mapping] Nicolin-1 B2R7Q3 [Target identity:100%; Query identity:100%] HCG2001997, isoform CRA_c; cDNA FLJ36929 fis, clone BRACE2005231, highly similar to Nicolin-1; cDNA, FLJ93554, Homo sapiens nicolin 1 (NICN1), mRNA Show all	Predicted intracellular proteins Show all	GO:0005634 [nucleus] GO:0005874 [microtubule] Show all	213 aa 24.2 kDa	No	0
NICN1-006 ENSP00000402335 ENST00000436744	B4DX77 [Direct mapping] Nicolin-1; cDNA FLJ52908, highly similar to Nicolin-1 Show all	Predicted intracellular proteins Show all		175 aa 19.7 kDa	No	0
NICN1-201 ENSP00000478287 ENST00000615713	Q9BSH3 [Direct mapping] Nicolin-1 B2R7Q3 [Target identity:100%; Query identity:100%] HCG2001997, isoform CRA_c; cDNA FLJ36929 fis, clone BRACE2005231, highly similar to Nicolin-1; cDNA, FLJ93554, Homo sapiens nicolin 1 (NICN1), mRNA Show all	Predicted intracellular proteins Show all	GO:0005634 [nucleus] GO:0005874 [microtubule] Show all	213 aa 24.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.