Expression of SPINK7 in cancer - Summary

CANCER ATLAS

Gene description

Serine peptidase inhibitor, Kazal type 7 (putative)

Protein class

Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA036294

GENE INFORMATION
Gene name	SPINK7 (HGNC Symbol)
Synonyms	ECG2, ECRG2
Description	Serine peptidase inhibitor, Kazal type 7 (putative) (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q32
Chromosome location (bp)	148312419 - 148315922
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000145879 (version 83.38)
Entrez gene	84651
UniProt	P58062 (UniProt - Evidence at protein level)
neXtProt	NX_P58062
Antibodypedia	SPINK7 antibodies

PROTEIN BROWSER

SPINK7-001	SPINK7-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SPINK7-001 ENSP00000274565 ENST00000274565	P58062 [Direct mapping] Serine protease inhibitor Kazal-type 7 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004867 [serine-type endopeptidase inhibitor activity] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0010951 [negative regulation of endopeptidase activity] Show all	85 aa 9.2 kDa	Yes	0
SPINK7-005 ENSP00000427887 ENST00000523535	E5RFX6 [Direct mapping] Serine protease inhibitor Kazal-type 7 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	59 aa 6.6 kDa	No	0