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SPINK7

GENERAL INFORMATION

Gene name

 SPINK7

Gene description

 Serine peptidase inhibitor, Kazal type 7 (putative)

Protein class

 Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (esophagus, tonsil)
GTEx:Group enriched (vagina, esophagus, cervix, uterine)
FANTOM5:Group enriched (esophagus, cervix, uterine, tonsil)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA036294
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (esophagus, tonsil)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (vagina, esophagus, cervix, uterine)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (esophagus, cervix, uterine, tonsil)

GENE INFORMATION

Gene name

 SPINK7 (HGNC Symbol)

Synonyms

 ECG2, ECRG2

Description

 Serine peptidase inhibitor, Kazal type 7 (putative) (HGNC Symbol)

Entrez gene summary

Chromosome

 5

Cytoband

 q32

Chromosome location (bp)

 148312419 - 148315922

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000145879 (version 83.38)

Entrez gene

 84651

UniProt

 P58062 (UniProt - Evidence at protein level)

neXtProt

 NX_P58062

Antibodypedia

 SPINK7 antibodies

PROTEIN BROWSER
SPINK7-001
SPINK7-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SPINK7-001
ENSP00000274565
ENST00000274565
P58062 [Direct mapping]
Serine protease inhibitor Kazal-type 7
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   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0004867 [serine-type endopeptidase inhibitor activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0010951 [negative regulation of endopeptidase activity]
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 85 aa
9.2 kDa 		Yes 0
SPINK7-005
ENSP00000427887
ENST00000523535
E5RFX6 [Direct mapping]
Serine protease inhibitor Kazal-type 7
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
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 59 aa
6.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.