Expression of SLC2A12 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 2 (facilitated glucose transporter), member 12

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA031593

GENE INFORMATION
Gene name	SLC2A12 (HGNC Symbol)
Synonyms	GLUT12, GLUT8
Description	Solute carrier family 2 (facilitated glucose transporter), member 12 (HGNC Symbol)
Entrez gene summary	SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Rogers et al., 2002). This family of transporters show conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008]
Chromosome	6
Cytoband	q23.2
Chromosome location (bp)	133988697 - 134052636
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000146411 (version 83.38)
Entrez gene	154091
UniProt	Q8TD20 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8TD20
Antibodypedia	SLC2A12 antibodies

PROTEIN BROWSER

SLC2A12-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC2A12-001 ENSP00000275230 ENST00000275230	Q8TD20 [Direct mapping] Solute carrier family 2, facilitated glucose transporter member 12 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005351 [sugar:proton symporter activity] GO:0005355 [glucose transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0012505 [endomembrane system] GO:0015758 [glucose transport] GO:0015992 [proton transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0035428 [hexose transmembrane transport] GO:0046323 [glucose import] GO:0048471 [perinuclear region of cytoplasm] GO:0055085 [transmembrane transport] GO:1904659 [glucose transmembrane transport] Show all	617 aa 67 kDa	No	>9