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AGBL3

GENERAL INFORMATION

Gene name

 AGBL3

Gene description

 ATP/GTP binding protein-like 3

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Tissue enriched (testis)
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Antibody staining not consistent with RNA expression data.

Reliability score

 Uncertain based on 2 antibodies.
HPA020397 , HPA024150
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 AGBL3 (HGNC Symbol)

Synonyms

 CCP3, MGC32955

Description

 ATP/GTP binding protein-like 3 (HGNC Symbol)

Entrez gene summary

Chromosome

 7

Cytoband

 q33

Chromosome location (bp)

 134986508 - 135147963

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000146856 (version 83.38)

Entrez gene

 340351

UniProt

 Q8NEM8 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8NEM8

Antibodypedia

 AGBL3 antibodies

PROTEIN BROWSER
AGBL3-006
AGBL3-007
AGBL3-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
AGBL3-006
ENSP00000401220
ENST00000435976
F8W7R4 [Direct mapping]
Cytosolic carboxypeptidase 3
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Predicted intracellular proteins
Show all
GO:0004181 [metallocarboxypeptidase activity]
GO:0006508 [proteolysis]
GO:0008270 [zinc ion binding]
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 704 aa
82.1 kDa 		No 0
AGBL3-007
ENSP00000388275
ENST00000436302
Q8NEM8 [Direct mapping]
Cytosolic carboxypeptidase 3
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Enzymes
   Peptidases
   Metallopeptidases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0004181 [metallocarboxypeptidase activity]
GO:0005829 [cytosol]
GO:0006508 [proteolysis]
GO:0008270 [zinc ion binding]
GO:0035610 [protein side chain deglutamylation]
Show all
 920 aa
107 kDa 		No 0
AGBL3-008
ENSP00000412700
ENST00000455283
F8W6Y5 [Direct mapping]
Cytosolic carboxypeptidase 3
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Predicted intracellular proteins
Show all
 93 aa
10.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.