Tissue expression of LPAR4 - Summary - The Human Protein Atlas

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LPAR4

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	LPAR4
Gene description	Lysophosphatidic acid receptor 4
Protein class	G-protein coupled receptors Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (ovary)
GTEx:	Tissue enhanced (ovary)
FANTOM5:	Tissue enhanced (hippocampus, cerebellum)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA054951 , HPA055571
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (ovary)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (ovary)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (hippocampus, cerebellum)

GENE INFORMATION
Gene name	LPAR4 (HGNC Symbol)
Synonyms	GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9
Description	Lysophosphatidic acid receptor 4 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the lysophosphatidic acid receptor family. It may also be related to the P2Y receptors, a family of receptors that bind purine and pyrimidine nucleotides and are coupled to G proteins. The encoded protein may play a role in monocytic differentiation. [provided by RefSeq, Feb 2009]
Chromosome	X
Cytoband	q21.1
Chromosome location (bp)	78747709 - 78757094
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000147145 (version 83.38)
Entrez gene	2846
UniProt	Q99677 (UniProt - Evidence at protein level)
neXtProt	NX_Q99677
Antibodypedia	LPAR4 antibodies

PROTEIN BROWSER

LPAR4-001	LPAR4-002	LPAR4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LPAR4-001 ENSP00000408205 ENST00000435339	Q99677 [Direct mapping] Lysophosphatidic acid receptor 4 Show all	Transporters G-protein coupled receptors GPCRs excl olfactory receptors Lysolipids receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008289 [lipid binding] GO:0016021 [integral component of membrane] GO:0035727 [lysophosphatidic acid binding] GO:0070915 [lysophosphatidic acid receptor activity] Show all	370 aa 41.9 kDa	No	7
LPAR4-002 ENSP00000476460 ENST00000514744	V9GY74 [Direct mapping] Lysophosphatidic acid receptor 4 Show all	Predicted intracellular proteins Show all		45 aa 5.1 kDa	No	0
LPAR4-201 ENSP00000478261 ENST00000614823	Q99677 [Direct mapping] Lysophosphatidic acid receptor 4 Show all	Transporters G-protein coupled receptors GPCRs excl olfactory receptors Lysolipids receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008289 [lipid binding] GO:0016021 [integral component of membrane] Show all	370 aa 41.9 kDa	No	7

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.