Expression of SLC25A37 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 25 (mitochondrial iron transporter), member 37

Protein class

Predicted intracellular proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA045680

GENE INFORMATION
Gene name	SLC25A37 (HGNC Symbol)
Synonyms	MFRN, MFRN1, MSCP
Description	Solute carrier family 25 (mitochondrial iron transporter), member 37 (HGNC Symbol)
Entrez gene summary	SLC25A37 is a solute carrier localized in the mitochondrial inner membrane. It functions as an essential iron importer for the synthesis of mitochondrial heme and iron-sulfur clusters (summary by Chen et al., 2009 [PubMed 19805291]).[supplied by OMIM, Jan 2011]
Chromosome	8
Cytoband	p21.2
Chromosome location (bp)	23528805 - 23575463
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000147454 (version 83.38)
Entrez gene	51312
UniProt	Q9NYZ2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NYZ2
Antibodypedia	SLC25A37 antibodies

PROTEIN BROWSER

SLC25A37-001	SLC25A37-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC25A37-001 ENSP00000429200 ENST00000519973	Q9NYZ2 [Direct mapping] Mitoferrin-1 Show all	Transporters Electrochemical Potential-driven transporters MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005381 [iron ion transmembrane transporter activity] GO:0005743 [mitochondrial inner membrane] GO:0016021 [integral component of membrane] GO:0034755 [iron ion transmembrane transport] GO:0044281 [small molecule metabolic process] GO:0048250 [mitochondrial iron ion transport] GO:0055072 [iron ion homeostasis] Show all	338 aa 37.3 kDa	No	0
SLC25A37-013 ENSP00000428066 ENST00000523930	H0YAT5 [Direct mapping] Mitoferrin-1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0006810 [transport] GO:0016021 [integral component of membrane] Show all	153 aa 16.6 kDa	No	0