Fields »
ABOUT
HELP
BLOG
SLC25A37

GENERAL INFORMATION

Gene name

 SLC25A37

Gene description

 Solute carrier family 25 (mitochondrial iron transporter), member 37

Protein class

 Predicted intracellular proteins
Transporters

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and nuclear expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA045680
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 SLC25A37 (HGNC Symbol)

Synonyms

 MFRN, MFRN1, MSCP

Description

 Solute carrier family 25 (mitochondrial iron transporter), member 37 (HGNC Symbol)

Entrez gene summary

 SLC25A37 is a solute carrier localized in the mitochondrial inner membrane. It functions as an essential iron importer for the synthesis of mitochondrial heme and iron-sulfur clusters (summary by Chen et al., 2009 [PubMed 19805291]).[supplied by OMIM, Jan 2011]

Chromosome

 8

Cytoband

 p21.2

Chromosome location (bp)

 23528805 - 23575463

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000147454 (version 83.38)

Entrez gene

 51312

UniProt

 Q9NYZ2 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9NYZ2

Antibodypedia

 SLC25A37 antibodies

PROTEIN BROWSER
SLC25A37-001
SLC25A37-013

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC25A37-001
ENSP00000429200
ENST00000519973
Q9NYZ2 [Direct mapping]
Mitoferrin-1
Show all
Transporters
   Electrochemical Potential-driven transporters
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005381 [iron ion transmembrane transporter activity]
GO:0005743 [mitochondrial inner membrane]
GO:0016021 [integral component of membrane]
GO:0034755 [iron ion transmembrane transport]
GO:0044281 [small molecule metabolic process]
GO:0048250 [mitochondrial iron ion transport]
GO:0055072 [iron ion homeostasis]
Show all
 338 aa
37.3 kDa 		No 0
SLC25A37-013
ENSP00000428066
ENST00000523930
H0YAT5 [Direct mapping]
Mitoferrin-1
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0006810 [transport]
GO:0016021 [integral component of membrane]
Show all
 153 aa
16.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.