Expression of TRIM55 in cancer - Summary

CANCER ATLAS

Gene description

Tripartite motif containing 55

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA038793	HPA053691

GENE INFORMATION
Gene name	TRIM55 (HGNC Symbol)
Synonyms	MURF-2, RNF29
Description	Tripartite motif containing 55 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Chromosome	8
Cytoband	q13.1
Chromosome location (bp)	66126896 - 66175487
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000147573 (version 83.38)
Entrez gene	84675
UniProt	Q9BYV6 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BYV6
Antibodypedia	TRIM55 antibodies

PROTEIN BROWSER

TRIM55-001	TRIM55-002	TRIM55-003	TRIM55-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRIM55-001 ENSP00000323913 ENST00000315962	Q9BYV6 [Direct mapping] Tripartite motif-containing protein 55 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004871 [signal transducer activity] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0007165 [signal transduction] GO:0008270 [zinc ion binding] GO:0042802 [identical protein binding] Show all	548 aa 60.5 kDa	No	0
TRIM55-002 ENSP00000297348 ENST00000353317	Q9BYV6 [Direct mapping] Tripartite motif-containing protein 55 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004871 [signal transducer activity] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0007165 [signal transduction] GO:0008270 [zinc ion binding] GO:0042802 [identical protein binding] Show all	452 aa 50.8 kDa	No	0
TRIM55-003 ENSP00000332302 ENST00000350034	Q9BYV6 [Direct mapping] Tripartite motif-containing protein 55 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004871 [signal transducer activity] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0007165 [signal transduction] GO:0008270 [zinc ion binding] GO:0042802 [identical protein binding] Show all	241 aa 26.8 kDa	No	0
TRIM55-004 ENSP00000276573 ENST00000276573	Q9BYV6 [Direct mapping] Tripartite motif-containing protein 55 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0004871 [signal transducer activity] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0007165 [signal transduction] GO:0008270 [zinc ion binding] GO:0042802 [identical protein binding] Show all	540 aa 60.2 kDa	No	1