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TRIM55

GENERAL INFORMATION

Gene name

 TRIM55

Gene description

 Tripartite motif containing 55

Protein class

 Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (heart muscle, liver)
GTEx:Group enriched (heart muscle, skeletal muscle, testis, liver)
FANTOM5:Tissue enhanced (skeletal muscle, heart muscle, liver)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in heart and skeletal muscle, testis and fallopian tube.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

 Approved based on 2 antibodies.
HPA038793 , HPA053691
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (heart muscle, liver)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (heart muscle, skeletal muscle, testis, liver)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (skeletal muscle, heart muscle, liver)

GENE INFORMATION

Gene name

 TRIM55 (HGNC Symbol)

Synonyms

 MURF-2, RNF29

Description

 Tripartite motif containing 55 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

 8

Cytoband

 q13.1

Chromosome location (bp)

 66126896 - 66175487

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000147573 (version 83.38)

Entrez gene

 84675

UniProt

 Q9BYV6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BYV6

Antibodypedia

 TRIM55 antibodies

PROTEIN BROWSER
TRIM55-001
TRIM55-002
TRIM55-003
TRIM55-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TRIM55-001
ENSP00000323913
ENST00000315962
Q9BYV6 [Direct mapping]
Tripartite motif-containing protein 55
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0007165 [signal transduction]
GO:0008270 [zinc ion binding]
GO:0042802 [identical protein binding]
Show all
 548 aa
60.5 kDa 		No 0
TRIM55-002
ENSP00000297348
ENST00000353317
Q9BYV6 [Direct mapping]
Tripartite motif-containing protein 55
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0007165 [signal transduction]
GO:0008270 [zinc ion binding]
GO:0042802 [identical protein binding]
Show all
 452 aa
50.8 kDa 		No 0
TRIM55-003
ENSP00000332302
ENST00000350034
Q9BYV6 [Direct mapping]
Tripartite motif-containing protein 55
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0007165 [signal transduction]
GO:0008270 [zinc ion binding]
GO:0042802 [identical protein binding]
Show all
 241 aa
26.8 kDa 		No 0
TRIM55-004
ENSP00000276573
ENST00000276573
Q9BYV6 [Direct mapping]
Tripartite motif-containing protein 55
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0007165 [signal transduction]
GO:0008270 [zinc ion binding]
GO:0042802 [identical protein binding]
Show all
 540 aa
60.2 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.