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Most cancer tissues exhibited weak to moderate membranous and/or cytoplasmic staining. Several cases of colorectal, endometrial and thyroid cancers were strongly stained. Gliomas, lymphomas and renal cancers were negative.
GENE INFORMATION
Gene name
SURF4 (HGNC Symbol)
Synonyms
ERV29, FLJ22993, MGC102753
Description
Surfeit 4 (HGNC Symbol)
Entrez gene summary
This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein that interacts with endoplasmic reticulum-Golgi intermediate compartment proteins. Disruption of this gene results in reduced numbers of endoplasmic reticulum-Golgi intermediate compartment clusters and redistribution of coat protein I to the cytosol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
B7Z1G8 [Direct mapping] Surfeit 4, isoform CRA_b; Surfeit locus protein 4; cDNA FLJ50444, highly similar to Surfeit locus protein 4; cDNA FLJ61766, highly similar to Surfeit locus protein 4; cDNA, FLJ79379, highly similar to Surfeit locus protein 4
B7Z1G8 [Direct mapping] Surfeit 4, isoform CRA_b; Surfeit locus protein 4; cDNA FLJ50444, highly similar to Surfeit locus protein 4; cDNA FLJ61766, highly similar to Surfeit locus protein 4; cDNA, FLJ79379, highly similar to Surfeit locus protein 4
