Expression of RSU1 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Ras suppressor protein 1

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA025927

GENE INFORMATION
Gene name	RSU1 (HGNC Symbol)
Synonyms	FLJ31034, RSP-1
Description	Ras suppressor protein 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	p13
Chromosome location (bp)	16590611 - 16817528
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000148484 (version 83.38)
Entrez gene	6251
UniProt	Q15404 (UniProt - Evidence at protein level)
neXtProt	NX_Q15404
Antibodypedia	RSU1 antibodies

PROTEIN BROWSER

RSU1-001	RSU1-002	RSU1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RSU1-001 ENSP00000339521 ENST00000345264	Q15404 [Direct mapping] Ras suppressor protein 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005925 [focal adhesion] GO:0007165 [signal transduction] GO:0010811 [positive regulation of cell-substrate adhesion] GO:0034329 [cell junction assembly] GO:0043547 [positive regulation of GTPase activity] GO:0070062 [extracellular exosome] Show all	277 aa 31.5 kDa	No	0
RSU1-002 ENSP00000367154 ENST00000377921	Q15404 [Direct mapping] Ras suppressor protein 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0005925 [focal adhesion] GO:0007165 [signal transduction] GO:0007265 [Ras protein signal transduction] GO:0010811 [positive regulation of cell-substrate adhesion] GO:0034329 [cell junction assembly] GO:0043547 [positive regulation of GTPase activity] GO:0070062 [extracellular exosome] GO:2000179 [positive regulation of neural precursor cell proliferation] Show all	277 aa 31.5 kDa	No	0
RSU1-201 ENSP00000473588 ENST00000602389	Q15404 [Direct mapping] Ras suppressor protein 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005925 [focal adhesion] GO:0007165 [signal transduction] GO:0010811 [positive regulation of cell-substrate adhesion] GO:0034329 [cell junction assembly] GO:0043547 [positive regulation of GTPase activity] GO:0070062 [extracellular exosome] Show all	224 aa 25.5 kDa	No	0