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RSU1

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GENERAL INFORMATION

Gene name

 RSU1

Gene description

 Ras suppressor protein 1

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to vesicles.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Vesicles (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA025927
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to vesicles.

Main location

 Vesicles (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA025927 A-431 Vesicles
HPA025927 U-2 OS Vesicles
HPA025927 U-251 MG Vesicles

GENE INFORMATION

Gene name

 RSU1 (HGNC Symbol)

Synonyms

 FLJ31034, RSP-1

Description

 Ras suppressor protein 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq, Jul 2008]

Chromosome

 10

Cytoband

 p13

Chromosome location (bp)

 16590611 - 16817528

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000148484 (version 83.38)

Entrez gene

 6251

UniProt

 Q15404 (UniProt - Evidence at protein level)

neXtProt

 NX_Q15404

Antibodypedia

 RSU1 antibodies

PROTEIN BROWSER
RSU1-001
RSU1-002
RSU1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RSU1-001
ENSP00000339521
ENST00000345264
Q15404 [Direct mapping]
Ras suppressor protein 1
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005829 [cytosol]
GO:0005925 [focal adhesion]
GO:0007165 [signal transduction]
GO:0010811 [positive regulation of cell-substrate adhesion]
GO:0034329 [cell junction assembly]
GO:0043547 [positive regulation of GTPase activity]
GO:0070062 [extracellular exosome]
Show all
 277 aa
31.5 kDa 		No 0
RSU1-002
ENSP00000367154
ENST00000377921
Q15404 [Direct mapping]
Ras suppressor protein 1
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0005925 [focal adhesion]
GO:0007165 [signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0010811 [positive regulation of cell-substrate adhesion]
GO:0034329 [cell junction assembly]
GO:0043547 [positive regulation of GTPase activity]
GO:0070062 [extracellular exosome]
GO:2000179 [positive regulation of neural precursor cell proliferation]
Show all
 277 aa
31.5 kDa 		No 0
RSU1-201
ENSP00000473588
ENST00000602389
Q15404 [Direct mapping]
Ras suppressor protein 1
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005829 [cytosol]
GO:0005925 [focal adhesion]
GO:0007165 [signal transduction]
GO:0010811 [positive regulation of cell-substrate adhesion]
GO:0034329 [cell junction assembly]
GO:0043547 [positive regulation of GTPase activity]
GO:0070062 [extracellular exosome]
Show all
 224 aa
25.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.