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MTMR12

CANCER ATLAS

Gene description

 Myotubularin related protein 12

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA051333

GENE INFORMATION

Gene name

 MTMR12 (HGNC Symbol)

Synonyms

 3-PAP, 3PAP, FLJ20476, KIAA1682, PIP3AP

Description

 Myotubularin related protein 12 (HGNC Symbol)

Entrez gene summary

 Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

Chromosome

 5

Cytoband

 p13.3

Chromosome location (bp)

 32226994 - 32313009

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000150712 (version 83.38)

Entrez gene

 54545

UniProt

 Q9C0I1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9C0I1

Antibodypedia

 MTMR12 antibodies

PROTEIN BROWSER
MTMR12-001
MTMR12-002
MTMR12-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MTMR12-001
ENSP00000371577
ENST00000382142
Q9C0I1 [Direct mapping]
Myotubularin-related protein 12
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0019208 [phosphatase regulator activity]
GO:0050790 [regulation of catalytic activity]
GO:1901998 [toxin transport]
Show all
 747 aa
86.1 kDa 		No 0
MTMR12-002
ENSP00000264934
ENST00000264934
Q9C0I1 [Direct mapping]
Myotubularin-related protein 12
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0019208 [phosphatase regulator activity]
GO:0050790 [regulation of catalytic activity]
Show all
 637 aa
73.2 kDa 		No 0
MTMR12-003
ENSP00000280285
ENST00000280285
Q9C0I1 [Direct mapping]
Myotubularin-related protein 12
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0019208 [phosphatase regulator activity]
GO:0050790 [regulation of catalytic activity]
Show all
 693 aa
79.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.