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ENKUR

GENERAL INFORMATION

Gene name

 ENKUR

Gene description

 Enkurin, TRPC channel interacting protein

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (fallopian tube)
GTEx:Tissue enhanced (hypothalamus)
FANTOM5:Tissue enhanced (testis, pituitary gland)

Protein evidence

 Evidence at protein level

Protein expression

 Distinct expression in cilia of fallopian tube and bronchial epithelia.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data. Protein expression in respiratory epithelia can be correlated with lung RNA-seq data.

Reliability score

 Supported based on 3 antibodies.
HPA037593 , HPA037594 , HPA061503
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Bronchus

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (fallopian tube)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (hypothalamus)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis, pituitary gland)

GENE INFORMATION

Gene name

 ENKUR (HGNC Symbol)

Synonyms

 C10orf63, CFAP106, enkurin, MGC26778

Description

 Enkurin, TRPC channel interacting protein (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that interacts with calmodulin and several transient receptor potential canonical cation channel proteins. The encoded protein may function as an adaptor to localize signal transduction machinery to calcium channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

Chromosome

 10

Cytoband

 p12.1

Chromosome location (bp)

 24981979 - 25062279

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000151023 (version 83.38)

Entrez gene

 219670

UniProt

 Q8TC29 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8TC29

Antibodypedia

 ENKUR antibodies

PROTEIN BROWSER
ENKUR-002
ENKUR-003
ENKUR-004
ENKUR-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ENKUR-002
ENSP00000331044
ENST00000331161
Q8TC29 [Direct mapping]
Enkurin
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
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GO:0001669 [acrosomal vesicle]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0017124 [SH3 domain binding]
GO:0031514 [motile cilium]
GO:0097228 [sperm principal piece]
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 256 aa
29.5 kDa 		No 0
ENKUR-003
ENSP00000433763
ENST00000483339
L7N489 [Direct mapping]
Enkurin
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Predicted intracellular proteins
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 125 aa
14.4 kDa 		No 0
ENKUR-004
ENSP00000365541
ENST00000376363
Q5VV23 [Direct mapping]
Chromosome 10 open reading frame 63, isoform CRA_b; Enkurin
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Predicted intracellular proteins
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 255 aa
29.4 kDa 		No 0
ENKUR-201
ENSP00000478989
ENST00000615958
A0A087WUX1 [Direct mapping]
Enkurin
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Predicted intracellular proteins
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 194 aa
22.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.