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SLC25A31

GENERAL INFORMATION

Gene name

 SLC25A31

Gene description

 Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31

Protein class

 Predicted membrane proteins
Transporters

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)
FANTOM5:Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression

 Granular cytoplasmic expression in several cell types, e.g cells in seminiferous ducts and glandular cells of gastrointestinal tract.

DATA RELIABILITY

Data reliability
description

 Antibody staining not consistent with RNA expression data. Pending external verification. Nuclear staining observed and disregarded

Reliability score

 Uncertain based on 3 antibodies.
HPA015064 , HPA016841 , HPA071684
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 SLC25A31 (HGNC Symbol)

Synonyms

 ANT4, DKFZP434N1235

Description

 Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 (HGNC Symbol)

Entrez gene summary

 Mitochondrial ADP/ATP carriers, such as SLC25A31, are nuclear-coded mitochondrial proteins that catalyze the exchange of ATP generated in mitochondria by ATP synthase (see MIM 108729) against ADP produced in cytosol by most energy-consuming reactions (Dolce et al., 2005 [PubMed 15670820]).[supplied by OMIM, Mar 2008]

Chromosome

 4

Cytoband

 q28.1

Chromosome location (bp)

 127730378 - 127774299

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000151475 (version 83.38)

Entrez gene

 83447

UniProt

 Q9H0C2 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9H0C2

Antibodypedia

 SLC25A31 antibodies

PROTEIN BROWSER
SLC25A31-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC25A31-001
ENSP00000281154
ENST00000281154
Q9H0C2 [Direct mapping]
ADP/ATP translocase 4 ADP/ATP translocase 4, N-terminally processed
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Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
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GO:0005215 [transporter activity]
GO:0005634 [nucleus]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0016021 [integral component of membrane]
GO:0031514 [motile cilium]
GO:0055085 [transmembrane transport]
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 315 aa
35 kDa 		No 2

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.