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Most malignant cells displayed moderate cytoplasmic and nuclear positivity. A majority of hepatocellular carcinomas and thyroid cancers exhibited strong cytoplasmic immunoreactivity. Many cases of malignant melanomas, lung, renal and cervical cancers were weakly stained or negative.
GENE INFORMATION
Gene name
EPG5 (HGNC Symbol)
Synonyms
hEPG5, KIAA1632
Description
Ectopic P-granules autophagy protein 5 homolog (C. elegans) (HGNC Symbol)
Entrez gene summary
This gene encodes a large coiled coil domain-containing protein that functions in autophagy during starvation conditions. Mutations in this gene cause Vici syndrome. [provided by RefSeq, Aug 2015]
Q9HCE0 [Direct mapping] Ectopic P granules protein 5 homolog
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SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
