Expression of CDYL in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Chromodomain protein, Y-like

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA035578	CAB012249

GENE INFORMATION
Gene name	CDYL (HGNC Symbol)
Synonyms	CDYL1, DKFZP586C1622
Description	Chromodomain protein, Y-like (HGNC Symbol)
Entrez gene summary	Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
Chromosome	6
Cytoband	p25.1
Chromosome location (bp)	4706159 - 4955551
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000153046 (version 83.38)
Entrez gene	9425
UniProt	Q9Y232 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y232
Antibodypedia	CDYL antibodies

PROTEIN BROWSER

CDYL-001	CDYL-003	CDYL-006	CDYL-007	CDYL-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDYL-001 ENSP00000330512 ENST00000328908	Q9Y232 [Direct mapping] Chromodomain Y-like protein Show all	Enzymes ENZYME proteins Transferases Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003714 [transcription corepressor activity] GO:0003824 [catalytic activity] GO:0004402 [histone acetyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007283 [spermatogenesis] GO:0008152 [metabolic process] GO:0016573 [histone acetylation] GO:0035064 [methylated histone binding] GO:1903507 [negative regulation of nucleic acid-templated transcription] Show all	598 aa 66.5 kDa	No	0
CDYL-003 ENSP00000340908 ENST00000343762	Q9Y232 [Direct mapping] Chromodomain Y-like protein Show all	Enzymes ENZYME proteins Transferases Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003714 [transcription corepressor activity] GO:0003824 [catalytic activity] GO:0004402 [histone acetyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007283 [spermatogenesis] GO:0008152 [metabolic process] GO:0016573 [histone acetylation] GO:0035064 [methylated histone binding] GO:1903507 [negative regulation of nucleic acid-templated transcription] Show all	412 aa 45.1 kDa	No	0
CDYL-006 ENSP00000380718 ENST00000397588	Q9Y232 [Direct mapping] Chromodomain Y-like protein Show all	Enzymes ENZYME proteins Transferases Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003714 [transcription corepressor activity] GO:0003824 [catalytic activity] GO:0004402 [histone acetyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007283 [spermatogenesis] GO:0008152 [metabolic process] GO:0016573 [histone acetylation] GO:0035064 [methylated histone binding] GO:1903507 [negative regulation of nucleic acid-templated transcription] Show all	544 aa 60.6 kDa	No	0
CDYL-007 ENSP00000394076 ENST00000449732	Q9Y232 [Direct mapping] Chromodomain Y-like protein Show all	Enzymes ENZYME proteins Transferases Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003714 [transcription corepressor activity] GO:0003824 [catalytic activity] GO:0004402 [histone acetyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007283 [spermatogenesis] GO:0008152 [metabolic process] GO:0016573 [histone acetylation] GO:0035064 [methylated histone binding] GO:1903507 [negative regulation of nucleic acid-templated transcription] Show all	412 aa 45.1 kDa	No	0
CDYL-009 ENSP00000394740 ENST00000440139	C9JQG7 [Direct mapping] Chromodomain Y-like protein Show all	Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] Show all	171 aa 19.3 kDa	No	0