Tissue expression of CDYL - Summary - The Human Protein Atlas

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CDYL

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TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CDYL
Gene description	Chromodomain protein, Y-like
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous nuclear expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA035578 , CAB012249
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	CDYL (HGNC Symbol)
Synonyms	CDYL1, DKFZP586C1622
Description	Chromodomain protein, Y-like (HGNC Symbol)
Entrez gene summary	Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
Chromosome	6
Cytoband	p25.1
Chromosome location (bp)	4706159 - 4955551
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000153046 (version 83.38)
Entrez gene	9425
UniProt	Q9Y232 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y232
Antibodypedia	CDYL antibodies

PROTEIN BROWSER

CDYL-001	CDYL-003	CDYL-006	CDYL-007	CDYL-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDYL-001 ENSP00000330512 ENST00000328908	Q9Y232 [Direct mapping] Chromodomain Y-like protein Show all	Enzymes ENZYME proteins Transferases Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003714 [transcription corepressor activity] GO:0003824 [catalytic activity] GO:0004402 [histone acetyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007283 [spermatogenesis] GO:0008152 [metabolic process] GO:0016573 [histone acetylation] GO:0035064 [methylated histone binding] GO:1903507 [negative regulation of nucleic acid-templated transcription] Show all	598 aa 66.5 kDa	No	0
CDYL-003 ENSP00000340908 ENST00000343762	Q9Y232 [Direct mapping] Chromodomain Y-like protein Show all	Enzymes ENZYME proteins Transferases Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003714 [transcription corepressor activity] GO:0003824 [catalytic activity] GO:0004402 [histone acetyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007283 [spermatogenesis] GO:0008152 [metabolic process] GO:0016573 [histone acetylation] GO:0035064 [methylated histone binding] GO:1903507 [negative regulation of nucleic acid-templated transcription] Show all	412 aa 45.1 kDa	No	0
CDYL-006 ENSP00000380718 ENST00000397588	Q9Y232 [Direct mapping] Chromodomain Y-like protein Show all	Enzymes ENZYME proteins Transferases Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003714 [transcription corepressor activity] GO:0003824 [catalytic activity] GO:0004402 [histone acetyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007283 [spermatogenesis] GO:0008152 [metabolic process] GO:0016573 [histone acetylation] GO:0035064 [methylated histone binding] GO:1903507 [negative regulation of nucleic acid-templated transcription] Show all	544 aa 60.6 kDa	No	0
CDYL-007 ENSP00000394076 ENST00000449732	Q9Y232 [Direct mapping] Chromodomain Y-like protein Show all	Enzymes ENZYME proteins Transferases Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003714 [transcription corepressor activity] GO:0003824 [catalytic activity] GO:0004402 [histone acetyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007283 [spermatogenesis] GO:0008152 [metabolic process] GO:0016573 [histone acetylation] GO:0035064 [methylated histone binding] GO:1903507 [negative regulation of nucleic acid-templated transcription] Show all	412 aa 45.1 kDa	No	0
CDYL-009 ENSP00000394740 ENST00000440139	C9JQG7 [Direct mapping] Chromodomain Y-like protein Show all	Phobius predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] Show all	171 aa 19.3 kDa	No	0

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