Expression of PLEKHG4B in cancer - Summary

CANCER ATLAS

Gene description

Pleckstrin homology domain containing, family G (with RhoGef domain) member 4B

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA036274

GENE INFORMATION
Gene name	PLEKHG4B (HGNC Symbol)
Synonyms	KIAA1909
Description	Pleckstrin homology domain containing, family G (with RhoGef domain) member 4B (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	p15.33
Chromosome location (bp)	140258 - 189970
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000153404 (version 83.38)
Entrez gene	153478
UniProt	Q96PX9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96PX9
Antibodypedia	PLEKHG4B antibodies

PROTEIN BROWSER

PLEKHG4B-001	PLEKHG4B-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PLEKHG4B-001 ENSP00000283426 ENST00000283426	Q96PX9 [Direct mapping] Pleckstrin homology domain-containing family G member 4B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005089 [Rho guanyl-nucleotide exchange factor activity] GO:0035023 [regulation of Rho protein signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	1271 aa 139.7 kDa	No	0
PLEKHG4B-002 ENSP00000422493 ENST00000502646	Q96HN1 [Direct mapping] PLEKHG4B protein; Pleckstrin homology domain-containing family G member 4B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		421 aa 45.9 kDa	No	0