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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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CCSAP
  • premium

    TISSUE

  • CELL

  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Centriole, cilia and spindle-associated protein

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA028402
HPA043443

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Most tumour tissues were negative or weakly stained. A few cases of gliomas and thyroid cancers displayed moderate to strong cytoplasmic immunoreactivity while several colorectal and breast cancers, among other tumours showed weak staining.

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Gliomas displayed moderate to strong cytoplasmic positivity. Remaining cancer tissues were generally negative.

GENE INFORMATION

Gene name

CCSAP (HGNC Symbol)

Synonyms

C1orf96, CSAP, FLJ41471

Description

Centriole, cilia and spindle-associated protein (HGNC Symbol)

Entrez gene summary

Chromosome

1

Cytoband

q42.13

Chromosome location (bp)

229321005 - 229343294

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000154429 (version 83.38)

Entrez gene

126731

UniProt

Q6IQ19 (UniProt - Evidence at protein level)

neXtProt

NX_Q6IQ19

Antibodypedia

CCSAP antibodies

PROTEIN BROWSER

CCSAP-001
CCSAP-003
CCSAP-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCSAP-001
ENSP00000355648
ENST00000366687
Q6IQ19 [Direct mapping]
Centriole, cilia and spindle-associated protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005819 [spindle]
GO:0005929 [cilium]
GO:0005930 [axoneme]
GO:0007275 [multicellular organismal development]
GO:0030424 [axon]
GO:0035869 [ciliary transition zone]
GO:0036064 [ciliary basal body]
GO:0045995 [regulation of embryonic development]
GO:0060296 [regulation of cilium beat frequency involved in ciliary motility]
Show all
270 aa
30.2 kDa
No 0
CCSAP-003
ENSP00000355647
ENST00000366686
Q6IQ19 [Direct mapping]
Centriole, cilia and spindle-associated protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005819 [spindle]
GO:0005929 [cilium]
GO:0005930 [axoneme]
GO:0007275 [multicellular organismal development]
GO:0030424 [axon]
GO:0035869 [ciliary transition zone]
GO:0036064 [ciliary basal body]
GO:0045995 [regulation of embryonic development]
GO:0060296 [regulation of cilium beat frequency involved in ciliary motility]
Show all
156 aa
17.8 kDa
No 0
CCSAP-201
ENSP00000284617
ENST00000284617
Q6IQ19 [Direct mapping]
Centriole, cilia and spindle-associated protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005819 [spindle]
GO:0005929 [cilium]
GO:0005930 [axoneme]
GO:0007275 [multicellular organismal development]
GO:0030424 [axon]
GO:0035869 [ciliary transition zone]
GO:0036064 [ciliary basal body]
GO:0045995 [regulation of embryonic development]
GO:0060296 [regulation of cilium beat frequency involved in ciliary motility]
Show all
270 aa
30.2 kDa
No 0

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