Expression of FAM69A in cancer - Summary

CANCER ATLAS

Gene description

Family with sequence similarity 69, member A

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA015718	HPA017281

GENE INFORMATION
Gene name	FAM69A (HGNC Symbol)
Synonyms	FLJ23493
Description	Family with sequence similarity 69, member A (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the FAM69 family of cysteine-rich type II transmembrane proteins. These proteins localize to the endoplasmic reticulum but their specific functions are unknown. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Chromosome	1
Cytoband	p22.1
Chromosome location (bp)	92832737 - 92961522
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000154511 (version 83.38)
Entrez gene	388650
UniProt	Q5T7M9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5T7M9
Antibodypedia	FAM69A antibodies

PROTEIN BROWSER

FAM69A-001	FAM69A-201	FAM69A-202	FAM69A-203	FAM69A-204

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM69A-001 ENSP00000359333 ENST00000370310	Q5T7M9 [Direct mapping] Protein FAM69A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] Show all	428 aa 49 kDa	No	1
FAM69A-201 ENSP00000482478 ENST00000613047	A0A087WZ97 [Direct mapping] Protein FAM69A Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		403 aa 46 kDa	No	0
FAM69A-202 ENSP00000484866 ENST00000613902	A0A087X2C2 [Direct mapping] Protein FAM69A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		383 aa 43.5 kDa	No	0
FAM69A-203 ENSP00000483279 ENST00000615519	Q5T7M9 [Direct mapping] Protein FAM69A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] Show all	162 aa 19 kDa	No	1
FAM69A-204 ENSP00000482718 ENST00000616709	A0A087WZK6 [Direct mapping] Protein FAM69A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	369 aa 42.1 kDa	No	1